New drug discovery
Anticancer research and mechanism
Photosensitizing agent discovery and application
Cancer drug discovery
Molecular carcinogenesis of prostate cancer
DNA repair and cell cycle control
Molecular pathway of adipogenesis
Chairman, Associate Professor
Controlling mechanisms underlying allergic and non-allergic inflammation.
Screening and development of anti-allergic and anti-inflammation regimens.
Genomic and proteomic studies on signal transduction of leukocytes.
Design and development of recombinant protein with medicinal potential.
Drug development and mechanism studies of anti-hepatitis C virus and anti-dengue virus from natural products or small molecules. Development of drug screening system targeting viral internal ribosomal entry site (IRES), viral protease, or viral RNA-dependent RNA polymerase. In addition, comprehensive investigation of the molecular mechanism of antiviral drug using pharmacoproteomic or pharmacogenomic approach.
Jeff Yi-Fu Chen
The molecular mechanism of drug resistance in oral cancer.
The molecular mechanism of betel quid-induced oral carcinogenesis.
The molecular mechanism of betel quid addiction and development of chemoprevention in oral cancer.
Investigation and applications in anticancer drug screening.
The modulation of mRNA exporting in tumorigenesis
Anti-cancer drugs screening using zebrafish models.
Computational medicinal chemistry
Computer Drug Virtual Screening
Liquid chromatography and mass spectrometry
Polymer and nanocomposites
Zebrafish as model in biomedical research