聯絡方式:

• 研究室: N1022 (實驗室: N1020), 第一教學大樓 (點我，實驗室語音簡介) 
• 電話: +886-7-3121101 ext. 2368    傳真: +886-7-3125339    E-mail: cchiu@kmu.edu.tw
• Researchgate: https://www.researchgate.net/profile/Chien_Chih_Chiu/
• ORCID: http://orcid.org/0000-0001-7307-2468

 

 

學經歷:

• 中山大學生物系 理學士 (1996) 及生物科學系碩士 (1998)
• 臺灣師範大學生命科學系理學博士 (2004) 及博士後研究員 (2004-2005)
• 高雄師範大學生物科技學系 兼任助理教授 (2006)
• 高雄醫學大學生物科技學系 助理教授 (2005-2011) /副教授 (2011- 2014) / 教授 (2014.09 - Present)
• 高雄醫學大學附設醫院 轉譯醫學研究中心 兼任副研究員 (2014)
• 高雄醫學大學醫學研究所 合聘教授 (2016.08 - Present)
• 中山大學生物科學系 合聘教授 ( 2016.08 - Present) 

• 高雄醫學大學附設醫院 臨床醫學研究中心 兼任研究員 (2017.08 - Present)

主負責授課科目：

基因體學與蛋白質體學

腫瘤生物學

書報討論 

專題研究 (大學三年級與四年級)

實驗室實習 (大學部二年級)

臨床試驗微學程負責教師 [連結學校學程中心] 本系有相當多畢業生從事臨床試驗專員工作，鼓勵有興趣的同學們申請學程，在校內即預先充實自我，提早強化職場競爭力!!

- 微學程介紹 (修滿必要學分將申請微學程證書，並註記所通過之修課科目)

- 課程規劃及要求

- 微學程心得

 (108學年修課學生回饋) 首先想先感謝高醫校方無償提供系上課程外，如此多元化的學分學程/微學程之課程，讓我們學生能以探索自己系所外專業領域之興趣，可以慢慢了解自己喜歡甚麼，以及對於可能適合從事甚麼領域……等的專業興趣培養。更重要的是，選修了學分學程及學分微學程，讓我們學生在大學經歷四年畢業後，能比同期學生多了更多競爭力。 我選擇選修的學分學程是「臨床試驗微學分學程」，這領域的學分學程課程與系上專業領域不盡相同，讓我自己的課業壓力有強大的挑戰，但也因此拓展開闊不同領域的知識，其中一門公衛系王姿乃教授開授的選修「流行病學」，讓我對此方面專業特別印象深刻，師長講解淺顯易懂，因應武漢肺炎疫情時事，在閱讀新聞或媒體資訊時也能看得懂些專有名詞的意義，相當實用。另外，在生物系陳炤杰教授開授的選修「試驗設計」、「試驗設計實習」也是受益良多，小班制的教學使我們每個學生能在課堂的軟體操作上即時接受老師的指導。

 

講義下載 (請暫時到 e-learning 區下載)：

l   大學部課程

普通生物學

普通生物學實驗

服務學習

電腦生物

分子生物學

自由基生物學

基因體及蛋白質體學

腫瘤生物學

l   研究所課程

腫瘤生物學特論

訊息傳遞特論

 研究興趣:

• 癌細胞抗藥機制
• 抗癌藥物篩選與機制探討
•  發展癌細胞致敏化策略

我們實驗室主要探索台灣常見的癌症包括肝癌、乳癌及非小細胞肺癌如何對臨床藥物產生抗性，

希望透過了解癌細胞產生抗藥性機制進行預防，或發展使癌細胞對臨床藥物重新致敏化(Chemosensitizer)的策略。

除了傳統的細胞凋亡(Apoptosis)，我們也對新穎程序性細胞死亡鐵凋亡(Ferroptosis)、程序性壞死(Necroptosis)及細胞自噬 (autophagic cell death) 有興趣，希望能運用癌細胞本身特性以誘導細胞死亡以抑制癌細胞。.

 

 我們也與臨床教師(醫師) 合作進行包括肝癌與眼部退化預防

1.探討薑黃素衍生物於藍光照射視網膜色素上皮層細胞的保護機制

 

糖尿病造成的視網膜損傷之小分子預防

 

說明：利用氯奎寧( Chloroquine)破壞細胞自噬能產生肺癌細胞致敏效果[全文]

說明：喹啉小分子可以透過調控ERK 活性強度達到抑制肺癌移行能力或誘導凋亡 [全文]

- 與醫化系陳義龍教授、藥學系曾志華教授合作成果。

 

 

招募實驗室生力軍！　歡迎主動積極有耐心、願意學習的同學加入我們！

（校內外皆可不限系級，只要有熱誠肯吃苦都歡迎! 外校同學歡迎暑期實習）

 歡迎申請暑期研究計畫徵求中。名額有限，意者從速 (5/29/2020 截止) - [詳見本校研發處網站] 

  

 

期刊論文: (可連結科技部查看最新論文) 

Publication since 2015 

1.  Hurng-Wern Huang, Yung-Ding Bow, Chia-Yih Wang, Yen-Chun Chen, Pei-Rong Fu, Kuo‑Feng Chang, Tso-Wen Wang, Chih-Hua Tseng, Yeh-long Chen *, and Chien-Chih Chiu*(2020, May)* DFIQ, a novel quinoline derivative shows anticancer potential by inducing apoptosis and autophagy in NSCLC cell and in vivo zebrafish xenograft models. Cancers 12(5), 1348. [全文]

2.   Peng SY, Hsiao CC, Lan TH, Yen C, Farooqi AA, Cheng CM, Tang JY, Yu TJ, Yeh YC, Chuang YT, Chien-Chih Chiu* and Chang HW* (2020, Jan). Pomegranate extract inhibits migration and invasion of oral cancer cells by downregulating matrix metalloproteinase-2/9 and epithelial-mesenchymal transition. Environmental Toxicology, 35(6):673-678. 

3.    Wangta Liu, Chang-Yi Wu, Mei-Jei Lu, Yung-Jen Chuang, Eing Mei Tsai, Steve Leu, I-Ling Lin, Chih-Jan Ko*, Chien-Chih Chiu*, and Wen-Tsan Chang* (2020, Jan). Phenoxyphenol Compound 4-HPPP Selectively Induces Antiproliferation Effects and Apoptosis in Human Lung Cancer Cells through Aneupolyploidization and ATR DNA Repair Signaling. Oxidative Medicine and Cellular Longevity, 7;2020:5167292.

4.    Yen-Yun Wang; Ling-Yi Xiao; Pao‐Chu Wu; Yuk‐Kwan Chen; Steven Lo; Stephen Chu‐Sung Hu; Yi-Hua Chen; Charles Chien-Chih Chiu; Shyng-Shiou Yuan* (2020, Jan). Orabase-formulated gentian violet effectively improved oral potentially malignant disorder in vitro and in vivo. Biochemical Pharmacology, (171), 13713.

5.    Wangta Liu, Yu-Lun Lo, Chin Hsu, Yi-Ting Wu, Zi-Xian Liao, Wen-Jeng Wu, Yi-Jou Chen, Chieh Kao, Chien-Chih Chiu*, and Li-Fang Wang*Contributed to this work equally. (2019, Sep). CS-PEI/Beclin-siRNA Downregulate Multidrug Resistance Proteins and Increase Paclitaxel Therapeutic Efficacy against NSCLC. Molecular Therapy — Nucleic Acids, 6; 17: 477–490.

6.    Chen CH, Hsu SY, Chien-Chih Chiu, Leu S* (2019, Aug). Exosomal miR-21 mediates the protective effect of cardiomyocytes-derived conditioned medium on ameliorating myocardial infarction in rats. Cells, 19;8(8).

7.    Suen JL1, Chang Y, Shiu YS, Hsu CY, Sharma P, Chien-Chih Chiu, Chen YJ, Hour TC, Tsai EM* (2019, Aug). IL-10 from plasmacytoid dendritic cells promotes angiogenesis in the early stage of endometriosis. The Journal of Pathology, 249(4):485-497.

8.    Sheng-Kai Hsu†, Chien-Chih Chiu†, Hans-Uwe Dahms, Chon-Kit Chou, Chih-Mei Cheng, Wen-Tsan Chang, Kai-Chun Cheng, Hui-Min David Wang and I-Ling Lin 2*. † Equal contribution. (2019, May). Unfolded Protein Response (UPR) in Survival, Dormancy, Immunosuppression, Metastasis, and Treatments of Cancer Cells. International Journal of Molecular Sciences, 20(10), 2518. †Contributed equally

9.    Han-Lin Chou, Yi-Hsiung Lin, Wangta Liu, Chang-Yi Wu, Ruei-Nian Li, Hurng-Wern Huang, Chi-Hsien Chou, Shean-Jaw Chiou, Chien-Chih Chiu*. Combination therapy of chloroquine and C2-ceramide enhanced cytotoxicity in Lung cancer H460 and H1299 cells. Cancers. 2019. 11(3):370. 

10. Yi-Chen Wang, Xing-Yu Haung, Chien-Chih Chiu, Meng-Yi Lin, Wen-Hung Lin, Wen-Tsan Chang, Chung-Chih Tseng, Hui-Min David Wang. Inhibitions of melanogenesis via Phyllanthus emblica fruit extract powder in B16F10 cells. Food Bioscience. 2019. 28:177-182.

11. Chon-Kit Chou, Hurng-Wern Huang, Chun-Feng Yang, Hans-Uwe Dahms, Shih-Shin Liang, Tsu-Nai Wang, Po-Lin Kuo, Edward Hsi, Eing-Mei Tsai*, Chien-Chih Chiu*. Reduced camptothecin sensitivity of estrogen receptor-positive human breast cancer cells following exposure to di(2-ethylhexyl)phthalate (DEHP) is associated with DNA methylation changes. Environmental Toxicology.2019 34(4):401-414.

12. CM Chien, JC Yang, PH Wu, CY Wu, GY Chen, YC Wu, CK Chou, CH Tseng, YL Chen*, Li-Fang Wang*, Chien-Chih Chiu*. Phytochemical Naphtho[1,2-b] furan-4,5-dione Induced Topoisomerase II-mediated DNA Damage Response in Human Non-small-Cell Lung Cancer. Phytomedicine. 2019, 54: 109-119  

13. Feng-Chi Hsieh, Chun-Tzu Hung, Kai-Chun Cheng, Chang-Yi Wu, Yen-Chun Chen, and Yu-Jen Wu, Wangta Liu*, Chien-Chih Chiu*. Protective effects of Lycium barbarum extracts on UVB-induced damage in human retinal pigment epithelial cells accompanied by attenuating ROS and DNA damage. Oxid Med Cell Longev. 2018. Article ID 4814928  

14. YC. Chang, Y Fong, EM Tsai, YG Chang, HL Chou, CY Wu, YN Teng, TC Liu, SS Yuan and Chien-Chih Chiu*. Exogenous C8-ceramide induces apoptosis by over-production of ROS and the switch of superoxide dismutases SOD1 to SOD2 in human lung cancer cells. Int. J. Mol. Sci. 2018. 19(10), 3010.   

15. Chon-Kit Chou, Wangta Liu, Yu-Jie Hong, Hans-Uwe Dahms, Chen-Hao Chiu, Wen-Tsan Chang, Ching-Ming Chien, Chia-Hung Yen, Yuan-Bin Cheng*, Chien-Chih Chiu*. Ethyl acetate extract of Scindapsus cf. hederaceus exerts the inhibitory bioactivity on human non-small cell lung cancer cells through modulating ER stress. Int. J. Mol. Sci. 2018, 19.7: 1832.

16. YH CHIU, SH HSU, HW HSU, KC HUANG, W LIU, CY WU, WP HUANG, JEFF YF CHEN, BH CHEN and Chien-Chih Chiu*. Human lung cancer cells can be sensitized to camptothecin by modulating autophagy. Int J Oncol. 2018, 53.5: 1967-1979.  

17. Chon-Kit Chou, Ya-Ting Yang, Ho-Chun Yang, Shih-Shin Liang, Tsu-Nai Wang, Po-Lin Kuo, Hui-Min David Wang, Eing-Mei Tsai*, Chien-Chih Chiu*. The impact of Bis(2-ethylhexyl) phthalate (DEHP) on cancer progression. Archivum Immunologiae et Therapiae Experimentalis. 2017 66.3: 183-197.

18. Yi-Chun Song, Bao-Jueng Wu, Chien-Chih Chiu, Chun-Lin Chen, Jun-Qing Zhou, Shuo-Rong Liang, Chang-Yih Duh, Ping-Jyun Sung, Zhi-Hong Wen, Chang-Yi Wu*. Coral-Derived Natural Marine Compound GB9 Impairs Vascular Development in Zebrafish. International Journal of Molecular Sciences. 2017 Aug 3;18(8)  

19. WT Chang, W Liu, YH Chiu, BH Chen, SC Chuang, YC Chen, YT Hsu, MJ Lu, SJ Chiou, CK Chou and Chien-Chih Chiu*. A 4-Phenoxyphenol Derivative Exerts Inhibitory Effects on Human Hepatocellular Carcinoma Cells through Regulating Autophagy and Apoptosis Accompanied by Downregulating α-Tubulin Expression. Molecules, 2017, 22,854. 

20. Chang WT, Fong Y, Chuang SC, Chou CK, Chou HL, Yang CF, Tseng CH, Chen YL, Chien-Chih Chiu*. 9-bis[2-(pyrrolidin-1-yl)ethoxy] -6-{4-[2-(pyrrolidin-1-yl) ethoxy]phenyl}-11H-indeno [1,2-c]quinolin-11-one (BPIQ), a quinoline derivative inhibits human hepatocellular carcinoma cells by inducing ER stress and apoptosis. Anticancer Agents Med Chem.2017;17(5):692-700. 

21. Wen-Tsan Chang, Wangta Liu, Yi-Han Chiu, Bing-Hung Chen, Shih-Chang Chuang , Yen-Chun Chen, Yun-Tzh Hsu, Mei-Jei Lu, Shean-Jaw Chiou, Chon-Kit Chou and Chien-Chih Chiu*. A 4-Phenoxyphenol Derivative Exerts Inhibitory Effects on Human Hepatocellular Carcinoma Cells through Regulating Autophagy and Apoptosis Accompanied by Downregulating α-Tubulin Expression. Molecules. 2017 May 21;22(5)

22. Chon-Kit Chou, Chin-Ju Tang, Han-Lin Chou, Chun-Yen Liu, Ming-Chong Ng, Yu-Ting Chang, Shyng-Shiou F. Yuan, Eing-Mei Tsai, Chien-Chih Chiu*. The Potential Role of Krüppel-Like Zinc Finger Protein Glis3 in Genetic Diseases and Cancers. Arch Immunol Ther Exp (Warsz). 2017 May 18

23. Hsueh-Wei Chang, Wen-DerWang, Chien-Chih Chiu, Chiou-Hua Chen, Yi-Shan Wang, Zih-Ying Chen, Wangta Liu, Ming-Hong Tai, Zhi-Hong Wen and Chang-Yi Wu*. Ftr82 Is Critical for Vascular Patterning during Zebrafish Development. Int J Mol Sci. 2017 Jan 13;18(1).

24. Fong Y, Wu CY, Chang KF, Chen BH, Chou WJ, Tseng CH, Chen YC, Wang HD, Chen YL, Chien-Chih Chiu*. Dual roles of extracellular signal-regulated kinase (ERK) in quinoline compound BPIQ-induced apoptosis and anti-migration of human non-small cell lung cancer cells. Cancer Cell Int. 2017 Mar 7;17:37.

25. Huang PC, Chien-Chih Chiu, Chang HW, Wang YS, Hsiu HH, Song YC, Wen ZH, Tai MH and Wu CY*. PrdxI encode peroxiredoxin is important for vascular development in zebrafish. FEBS Lett. 2017 Mar;591(6):889-902.

26. Chon-Kit Chou, Yu-Ting Chang, Michal Korinek, Yei-Tsung Chen, Ya-Ting Yang, Steve Leu, I-Ling Lin, Chin-Ju Tang, Chien-Chih Chiu*. The regulations of deubiquitinase USP15 and its pathophysiological mechanisms in diseases. Int J Mol Sci. 2017 Feb 24;18(3)

27. Yuli C. Chang,  Chien-Chih Chiu, Chung-Yee Yuo, Wen-Ling Chan, Ya-Sian Chang, Wen-Hsin Chang, Shou-Mei Wu, Han-Lin Chou, Ta-Chi Liu, Chi-Yu Lu, Wen-Kuang Yang, Jan-Gowth Chang*. An XIST-related small RNA regulates KRAS G-quadruplex formation beyond X-inactivation. Oncotarget. 2016. doi: 10.18632/oncotarget.13433.

28. Chou HL, Fong Y, Lin HH, Tsai EM, Chen YF, Chang WT, Wu CY, Wang HM, Huang HW and  Chien-Chih Chiu * “An acetamide derivative as a camptothecin sensitizer for human non-small cell lung cancer cells through increased oxidative stress and JNK activation". Oxid Med Cell Longev. 2016. Article ID 9128102. 

29. Fong Y, Tang CC, Hu HT, Fang HY, Wu CY, Yuan SS, Wang HM, Chen YC, Teng YN and Chien-Chih Chiu *. The inhibitory effect of trans-Ferulic acid on proliferation and migration of human lung cancer cells through modulating endogenous ROS and beta-catenin activity. Chinese Medicine, 2016 11:45. eCollection 2016. 

30. Liang SS, Wang TN, Chien-Chih Chiu, Kuo PL, Huang MF, Liu MC, Tsai EM. (2016, Feb). Reductive amination-assisted quantitation of tamoxifen and its metabolites by liquid phase chromatography tandem mass spectrometry. Journal of Chromatography A, 1434:64-9. 

31. Liu YS, Cheng RY, Lo YL, Hsu C, Chen SH, Chien-Chih Chiu*, Wang LF*. (*Corresponding authors) (2016, Jan). Distinct CPT-induced deaths in lung cancer cells caused by clathrin-mediated internalization of CP micelles. Nanoscale, 8(6):3510-22. 

32. Chien-Chih Chiu*, Kuo-Feng Chang, Bing-Hung Chen, Han-Lin Chou, Chih-Hua Tseng, Yao Fong, Tzu-Fun Fu, Hsueh-Wei Chang, Chang-Yi Wu, Eing-Mei Tsai, Shinne-Ren Lin and Yeh-Long Chen* (*Corresponding authors) (2015, Dec). BPIQ, a novel synthetic quinoline derivative, inhibits growth and induces mitochondrial apoptosis of lung cancer cells in vitro and in zebrafish xenograft model. BMC Cancer, 15:962. 

33. Chih-Hua Tseng, You-Ren Chen, Cherng-Chyi Tzeng, Wangta Liu, Chon-Kit Chou, Chien-Chih Chiu*, Yeh-Long Chen* (*Corresponding authors) (2015, Nov). Discovery of Indeno[1,2-b]quinoxaline Derivatives as Potential Anticancer Agents. European Journal of Medicinal Chemistry. 

34. Kai-Chun Cheng, Chun-Tzu Hung, Kuo-Jen Chen, Wen-Chuan Wu, Jau-Ling Suen, Cheng-Hsien Chang, Chi-Yu Lu, Chih-Hua Tseng, Yeh-Long Chen, Chien-Chih Chiu* (2015, Aug). Quinoline-Based Compound BPIQ Exerts Anti-Proliferative Effects on Human Retinoblastoma Cells via Modulating Intracellular Reactive Oxygen Species. Arch Immunol Ther Exp (Warsz). 2015 Apr;64(2):139-47 

35. Chon-Kit Chou, Chang-Yi Wu, Jeff Yi-Fu Chen, Ming‐Chong Ng, Hui-Min David Wang, Jen-Hao Chen, Shyng-Shiou F Yuan, Eing-Mei Tsai, Jan-Gowth Chang*, Chien-Chih Chiu* (2015, Jul). BubR1 Acts as a Promoter in Cellular Motility of Human Oral Squamous Cancer Cells through Regulating MMP-2 and MMP-9. International Journal of Molecular Sciences, 16(7):15104-17. 

36. Wu, Pei-Fang; , Chien-Chih Chiu; Chen, Chung-Yi. Wang, Hui-Min. (2015, Jul). 7-Hydroxydehydronuciferine induces human melanoma death via triggering autophagy and apoptosis. Experimental Dermatology. 

 

Conferences 

·   Han-Lin Chou, Hurng-Wern Huang, Chien-Chih Chiu*. Chloroquine synergistically promotes C2-ceramide-induced apoptosis of non-small cell lung cancer cells via inhibiting sirt1 expression. 2013 Taiwan Zebrafish Symposium Dec. 7. Institute of Biomedical Sciences Academia Sinica. #P22. (The best poster award).  台灣斑馬魚研討會

·      Mei-Jei Lu and Chien-Chih Chiu*. The effect of Akt-targeting compounds on proliferation and apoptosis of lung cancer cells in zebrafish xenografts.2013 Taiwan Zebrafish Symposium Dec. 7. Institute of Biomedical Sciences Academia Sinica.#P23. 台灣斑馬魚研討會

·      Chien Chih, Chiu and  Bing-Hung Chen*. Anti-allergic activity of grape seed extract (GSE) on RBL-2H3 mast cells. The 19th Symposium of Young Asian Biochemical Engineer’s Community (YABEC). (ORAL#1). 2013. Urumqi, China.

·       Chon Kit, Chou, Chien Chih, Chiu*. The 19th Symposium of Young Asian Biochemical Engineer’s Community (YABEC). (POSTER#PD1). YABEC 2013. Urumqi, China. (YABEC *best poster award)
Han Lin, Chou, Chien Chih, Chiu*. The 19th Symposium of Young Asian Biochemical Engineer’s Community (YABEC). (POSTER#PD2). 2013. Urumqi, China. 

·       Yin-Chieh Lin, Jeff Yi-Fu Chen, Chien-Chih Chiu*. The inhibitory effects of sirtinol, a sirtuin inhibitor on invasion of non-small cell lung cancer cells via Src signaling. The 18th Symposium of Young Asian Biochemical Engineer’s Community (YABEC) 2012. (ORAL: O-CD-7).

·       Pin-Hsuan Wu, Jeff Yi-Fu Chen, Yeh-Long Chen, Chien-Chih Chiu*. Naphtho[1,2-b] furan-4,5-dione, a naphthoquinone derivative induces anti-cell growth and anti-migration in non-small cell lung cancer by inhibiting topoisomerase II. Bio-IT WORLD ASIA in Marina Bay Sands Hotel, Singapore, in June 6-8, 2012.(*corresponding). (POSTER #6) Session of Drug Discovery and Bioinformatics.

·       Yuli C. Chang, Shih-Ya Hung, Chien-Chih Chiu, Wen-Lin Chan, Wen-Hsin Chang, Shou-Mei Wu, Ya-Sian Chang, Chung-Yee Yuo, Ta-Chih Liu, Wen-Kuang Yang, Jan-Gowth Chang*. Participation of a XIST-related small RNA in the formation of the K-RAS G-quadruplex. Non-Coding RNAs (Z1) Keystone symposia conference. Snowbird, Utah, USA, in March 31-April 5. 2012

·       Yin-Chieh Lin, Han-Lin Chou, Chien-Chih Chiu＊. The inhibitory effects of sirtuin1 inhibitor, sirtinol on migration and anchorage independent growth of lung cancer cells. (POSTER #85) SCMB2012. 第20 屆細胞及分子生物新知研討會 (*corresponding)

·       Han-Lin Chou, Feng-Wei Chen, Xin-Ping Tang, Hurng-Wern Huang＊, Chiu, Chien-Chih＊. The synergistic effect of C2-ceramide in Doxorubicin was induced senescence of non-small-cell lung cancer (NSCLC). (POSTER #57) SCMB2012. 第20 屆細胞及分子生物新知研討會 (*corresponding)

·       Chon Kit Chou, Han-Lin Chou, Feng-Wei Chen, Chien-Chih Chiu*.The Novel Function of BubR1 in Migration Ability of Non-Small Cell Lung Cancer Cells. (POSTER #121) SCMB2012. 第20 屆細胞及分子生物新知研討會(*corresponding)

·       Huei-Ting Hu, Hsueh-Wei Chang*, Lian-Je Hwang, Hsin-Yu Fang, Chien-Chih Chiu*. Effect of ferulic acid on anti-oxidation and cell proliferation of human lung cancer cells. (POSTER #95) SCMB 2012. 第20 屆細胞及分子生物新知研討會. (*corresponding)

·       Pin-Hsuan Wu, Chien-Chih Chiu*, Yeh-Long Chen, Hsueh-Wei Chang. A novel naphthoquinone derivative-induced apoptosis and growth inhibition of human non-small cell lung cancer (NSCLC). (POSTER #27) SCMB2012. 第20 屆細胞及分子生物新知研討會. (*corresponding)

·       Chiu-Chien Chiu*, Chon-Kit Chou, Han-Lin Chou. Goniothalamin inhibits growth of human lung cancer cells through DNA damage, apoptosis and reduced migration ability. (Oral and POSTER) (POSTER # F14). The 17th Symposium of Young Asian Biochemical Engineer’s Community (YABEC) in Incheon, Korea in Oct 7-9,2011. (*corresponding)

·       Kuo-Feng Chang, Hsueh-Wei Chang, Tso-Wen Wang, Chih-Hua Tseng, Yeh-Long Chen, Chien-Chih Chiu*. The mechanistic study of quinoline-derivative-induced apoptosis and growth inhibition of lung cancer.(POSTER #160) SCMB 2011. 第19屆細胞及分子生物新知研討會. (*corresponding)

·       Kuo-Feng Chang, Hsueh-Wei Chang, Wan-Ju Chou, Chih-Hua Tseng, Yeh-Long Chen, Chien-Chih Chiu*. The quinoline-derivative DFIQ induced apoptosis and growth inhibition of lung cancer. SCMB 2011. 第19屆細胞及分子生物新知研討會. (*corresponding)

·       Han-Lin Chou, Hsueh-Wei Chang, Pi-Chuan Hsieh, Xin-Ping Tang, Feng-Wei Chen, Hurng-Wern Huang*,Chiu, Chien-Chih*. Role of exogenous ceramides in modulating the expression of human type III deacetylase SIRT-1 and SIRT-2 of human non-small cell lung cancer (NSCLC) cells. (POSTER #86) SCMB 2011.第19屆細胞及分子生物新知研討會. (*corresponding)

·       Yin-Chieh Lin, Jeff Yi-Fu Chen, Hsueh-Wei Chang*, Chien-Chih Chiu*. The modulation of cell proliferation induced by exogenous ceramide in human breast cancer cells. (POSTER #114) SCMB 2011. 第19屆細胞及分子生物新知研討會. (*corresponding)

·       Huei-Ting Hu, Hsueh-Wei Chang, Lian-Je Hwang, Hsin-Yu Fang, Chien-Chih Chiu*. Effect of feruloyl xylo-oligosaccharides on antioxidant activity and cell migration in human lung cancer H1299 cells. (POSTER #133) SCMB 2011. 第19屆細胞及分子生物新知研討會. (*corresponding)

·       Pin-Hsuan Wu, Chien-Chih Chiu*, Yeh-Long Chen and Hsueh-Wei Chang*. NFD inhibits cell proliferation and migration of human non-small cell lung cancer (NSCLC) cell through DNA damage and reduced migration ability. (POSTER #50) SCMB 2011. 第19 屆細胞及分子生物新知研討會. (*corresponding)

·       Chon-kit Chou, Han-Lin Chou, Pin-Hsuan Wu, Hsueh-Wei Chang* and Chien-Chih Chiu*. The effect of spindle assembly checkpoint kinase BubR1 on cellular migration in oral squamous cell carcinoma. (POSTER #171) SCMB 2011. 第19 屆細胞及分子生物新知研討會. (*corresponding)

·       Kuang-Jing Huang, Chien-Chih Chiu*, Fang-Rong Chang, Yang-Chang Wu, Hsueh-Wei Chang*. AN10 is a potential natural product-derived drug against oral cancer. SCMB 2011. 第19 屆細胞及分子生物新知研討會.(*corresponding)

·       Kuang-Jing Huang, Chien-Chih Chiu*, Fang-Rong Chang, Yang-Chang Wu, Hsueh-Wei Chang*. AN10 inhibits growth of human lung cancer cells through DNA damage, apoptosis and reduced migration ability. (POSTER #256) SCMB 2011. 第19屆細胞及分子生物新知研討會. (*corresponding)

·       Kuang-Jing Huang, Chien-Chih Chiu*, Fang-Rong Chang, Yang-Chang Wu, Hsueh-Wei Chang*. SCMB 2011. AN37 is a potential natural product-derived drug against oral cancer.第19屆細胞及分子生物新知研討會.

·       Jeff Yi-Fu Chen, Chien-Chih Chiu, Yu-Jen Wu, Hau-Ren Chen. Betel Quid Extract Promotes Oral Cancer Cell Migration by Activating a Muscarinic M4 Receptor-Mediated Signaling Cascade Involving ERK1/2 and SFKs. 4th World Congress of International Federation of Head and Neck Oncologic Societies in Seoul, Korea in June 15-19, 2010.

·       Guang-Jing Huang, Ming-Tz Tsai, Chon-Kit Chou, Chien-Chih Chiu, Yang-Chang Wu, Hsueh-Wei Chang. Growth inhibition of lung cancer cell using herb-derived compound AN10 based on cell migration analysisSCMB 2010. 第18屆分子生物學會冬令營

·       Yung-Lan Su, Yi-Han Lo, Wan-Yu Chen, Tsung-Lun Kuo, Jan-Gowth Chang*, Chien-Chih Chiu*.Characterization of ectopic expression of nuclear export factor (NXF) in human hepatoma cells Huh-7 (POSTER # P331) The Twenty-fourth Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan. (Mar. 21-22, 2009). 第24屆生物醫學聯合學術年會 (*corresponding)

·       Chien-Chih Chiu* (Oral Presentation # O46 ). Effects of ectopically expressed nuclear export factor (NXF) on cell migration and adhesion in human hepatoma cells. The Twenty-fourth Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, Mar. 21-22, 2009. 第24屆生物醫學聯合學術年會 (*oral and corresponding)

·       Pi-Chuan Hsieh, Chien-Chih, Chiu, Jan-Gowth Chang, Sheng-Fung Lin.BubR1 Gene Is Involved in Ceramide Induced Mitotic Arrest in Malignant Cancer Cells.(May 2007). 第12屆台灣癌症聯合學術年會

·       Ying-Chieh Chu, Kai-Li Su, Min-Tsui Wu, Chien-Chih Chiu*. The effects of caffeic acid in anticancer drug-induced human non-small cell lung cancer (NSCLC) cells. (Mar 2007). 第22屆生物醫學年會 (*corresponding)

 

流式細胞儀的工作原理以功能 https://www.youtube.com/watch?v=EQXPJ7eeesQ

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KMU 2021 Spring Admission for International Degree Students has been open on July 13, 2020.
Application period: July 13, 2020 - October 16, 2020
Online Application: https://admission.kmu.edu.tw

 

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