研究成果

 期刊論文: (可連結科技部查看最新論文) Publication since 2015 

1.    Wen-Tsan Chang†, Yung-Ding Bow†, Yen-Chun Chen, Chia-Yang Li, Jeff Yi-Fu Chen, Yi-Ching Chu, Yen-Ni Teng, Ruei-Nian Li, and Chien-Chih Chiu* (2021, Jan) The Phenoxyphenol Compound diTFPP mediates Exogenous C2-Ceramide Metabolism, inducing Cell Apoptosis accompanied by ROS Formation and Autophagy in Hepatocellular Carcinoma Cells. Antioxidants, 10(3), 394. 與附院臨床教師 張文燦醫師共同著作 (研究生鮑永定)

2.     Kai-Chun Cheng, Yun-Tzu Hsu, Wangta Liu, Huey-Lan Huang, Liang-Yu Chen, Chen-Xi He, Shwu-Jiuan Sheu, Kuo-Jen Chen, Po-Yen Lee, Yi-Hsiung Lin*, Chien-Chih Chiu* (2021, Jan). The role of oxidative stress and autophagy in blue light-induced damage to the retinal pigment epithelium in zebrafish in vitro and in vivo. Int. J. Mol. Sci. 29;22(3):1338. doi: 10.3390/ijms22031338. 與附院臨床教師 鄭凱駿醫師共同著作 (研究生許云慈)

2.    Chung Shou-Jie; Ganta Prasanna; Chang Yu-Lun; Kosuru Someswara; Chang Heng-Yi; Ding Shangwu; Chen, Hsuan-Ying*; Chien-Chih Chiu*; Wu Kuo-Hui* (2020, Dec). Titanium Complexes Bearing 2,6-Bis(o-hydroxyalkyl)pyridine Ligands in Vitro Cytotoxicity Against Triple-Negative Breast-Cancer Cells. Chinese Chemical Society. (Accepted).應化系陳喧應教授共同著作.

3.      Yu-Wen Kao, Sheng-Kai Hsu, Jeff Yi-Fu Chen, I-Ling Lin, Kuo-Jen Chen, Po-Yen Lee, Hui-Suan Ng, Chien-Chih Chiu*, Kai-Chun Cheng* (2020, Dec). Curcumin metabolite tetrahydrocurcumin in the treatment of eye diseases. Int. J. Mol. Sci. 2021, 22(1), 212; https://doi.org/10.3390/ijms22010212. (第一作者為醫學系高鈺雯同學/醫技系徐聖凱同學)與臨床教師 鄭凱駿醫師共同著作

4.      Wen-Tsan Chang, Yung-Ding Bow, Pei-Rong Fu, Chia-Yang Li, Chang-Yi Wu, Yi-Hua Chang, Yen-Ni Teng, Ruei-Nian Li, Mei-Chin Lu, Yi-Chang Liu*, Chien-Chih Chiu* (2020, Nov). A marine terpenoid, heteronemin, induces both the apoptosis and ferroptosis of hepatocellular carcinoma cells and involves the ROS and MAPK pathways. Oxid Med Cell Longev. (Accepted). 與附院臨床教師 張文燦醫師共同著作

5.  Feng-Jie Lai, Tsai-Wen Huang, Yu-Lun Chang, Heng-Yi Chang Chang, Wei-Yi Lu, Shangwu Ding, Hsuan Ying Chen*, Chien-Chih Chiu*, Kuo-Hui Wu* (2020, Jul). Titanium complexes bearing 2,6-Bis(o-hydroxyalkyl)pyridine ligands in the ring-opening polymerization of L-Lactide and ε-caprolactone. Polymer. 204, 122860.應化系陳喧應教授共著.

6.      Kai-Hsu Sheng, Wen-Tsan Chang, I-Ling Lin, Yih-Fung Chen, Nitin Balkrushna Padalwar, Kai-Chun Cheng, Yen-Ni Teng, Chi-huei Wang *, Chien-Chih Chiu* (2020, Jul). The role of necroptosis in ROS-mediated cancer therapies and its promising applications. Cancers, 12(8), 2185. (第一作者為醫技系 徐聖凱同學)

7.       Peng SY, Hsiao CC, Lan TH, Yen C, Farooqi AA, Cheng CM, Tang JY, Yu TJ, Yeh YC, Chuang YT, Chien-Chih Chiu* and Chang HW* (2020, Jun). Pomegranate extract inhibits migration and invasion of oral cancer cells by downregulating matrix metalloproteinase-2/9 and epithelial-mesenchymal transition. Environ. Toxicol, 35(6):673-678. 

8.      Hurng-Wern Huang, Yung-Ding Bow, Chia-Yih Wang, Yen-Chun Chen, Pei-Rong Fu, Kuo‑Feng Chang, Tso-Wen Wang, Chih-Hua Tseng, Yeh-long Chen*,and Chien-Chih Chiu* (2020, May)* DFIQ, a novel quinoline derivative shows anticancer potential by inducing apoptosis and autophagy in NSCLC cell and in vivo zebrafish xenograft models. Cancers 12(5), 1348. [全文]  與應用化學系 陳義龍教授共同著作

9.       Wangta Liu, Chang-Yi Wu, Mei-Jei Lu, Yung-Jen Chuang, Eing Mei Tsai, Steve Leu, I-Ling Lin, Chih-Jan Ko*, Chien-Chih Chiu*, and Wen-Tsan Chang* (2020, Jan). Phenoxyphenol Compound 4-HPPP Selectively Induces Antiproliferation Effects and Apoptosis in Human Lung Cancer Cells through Aneupolyploidization and ATR DNA Repair Signaling. Oxid Med Cell Longev, 7;2020:5167292.

11.      Wangta Liu, Yu-Lun Lo, Chin Hsu, Yi-Ting Wu, Zi-Xian Liao, Wen-Jeng Wu, Yi-Jou Chen, Chieh Kao, Chien-Chih Chiu*, and Li-Fang Wang*Contributed to this work equally. (2019, Sep). CS-PEI/Beclin-siRNA Downregulate Multidrug Resistance Proteins and Increase Paclitaxel Therapeutic Efficacy against NSCLC. Molecular Therapy — Nucleic Acids, 6; 17: 477–490. 

12.    Sheng-Kai Hsu†, Chien-Chih Chiu†, Hans-Uwe Dahms, Chon-Kit Chou, Chih-Mei Cheng, Wen-Tsan Chang, Kai-Chun Cheng, Hui-Min David Wang and I-Ling Lin 2*. † Equal contribution. (2019, May). Unfolded Protein Response (UPR) in Survival, Dormancy, Immunosuppression, Metastasis, and Treatments of Cancer Cells. Int. J. Mol. Sci, 20(10), 2518. †Contributed equally (第一作者為醫技系 徐聖凱同學/)

13.     Han-Lin Chou, Yi-Hsiung Lin, Wangta Liu, Chang-Yi Wu, Ruei-Nian Li, Hurng-Wern Huang, Chi-Hsien Chou, Shean-Jaw Chiou, Chien-Chih Chiu*. Combination therapy of chloroquine and C2-ceramide enhanced cytotoxicity in Lung cancer H460 and H1299 cells. Cancers. 2019. 11(3):370. (第一作者為 中山大學生物醫學研究所 周翰林)

14.    Chon-Kit Chou, Hurng-Wern Huang, Chun-Feng Yang, Hans-Uwe Dahms, Shih-Shin Liang, Tsu-Nai Wang, Po-Lin Kuo, Edward Hsi, Eing-Mei Tsai*, Chien-Chih Chiu*. Reduced camptothecin sensitivity of estrogen receptor-positive human breast cancer cells following exposure to di(2-ethylhexyl)phthalate (DEHP) is associated with DNA methylation changes. Environ. Toxicol, 2019 34(4):401-414. 與附院臨床教師 蔡英美醫師共同著作

15.    CM Chien, JC Yang, PH Wu, CY Wu, GY Chen, YC Wu, CK Chou, CH Tseng, YL Chen*, Li-Fang Wang*, Chien-Chih Chiu*. Phytochemical Naphtho[1,2-b] furan-4,5-dione Induced Topoisomerase II-mediated DNA Damage Response in Human Non-small-Cell Lung Cancer. Phytomedicine. 2019, 54: 109-119  

16.     Feng-Chi Hsieh, Chun-Tzu Hung, Kai-Chun Cheng, Chang-Yi Wu, Yen-Chun Chen, and Yu-Jen Wu, Wangta Liu*, Chien-Chih Chiu*. Protective effects of Lycium barbarum extracts on UVB-induced damage in human retinal pigment epithelial cells accompanied by attenuating ROS and DNA damage. Oxid Med Cell Longev. 2018. Article ID 4814928  

17.  YC. Chang, Y Fong, EM Tsai, YG Chang, HL Chou, CY Wu, YN Teng, TC Liu, SS Yuan, and Chien-Chih Chiu*. Exogenous C8-ceramide induces apoptosis by over-production of ROS and the switch of superoxide dismutases SOD1 to SOD2 in human lung cancer cells. Int. J. Mol. Sci. 2018. 19(10), 3010.   

18.   Chon-Kit Chou, Wangta Liu, Yu-Jie Hong, Hans-Uwe Dahms, Chen-Hao Chiu, Wen-Tsan Chang, Ching-Ming Chien, Chia-Hung Yen, Yuan-Bin Cheng*, Chien-Chih Chiu*. Ethyl acetate extract of Scindapsus cf. hederaceus exerts inhibitory bioactivity on human non-small cell lung cancer cells through modulating ER stress. Int. J. Mol. Sci. 2018, 19.7: 1832.

19.      YH CHIU, SH HSU, HW HSU, KC HUANG, W LIU, CY WU, WP HUANG, JEFF YF CHEN, BH CHEN, and Chien-Chih Chiu*. Human lung cancer cells can be sensitized to camptothecin by modulating autophagy. Int J Oncol. 2018, 53.5: 1967-1979.  

20.      Chon-Kit Chou, Ya-Ting Yang, Ho-Chun Yang, Shih-Shin Liang, Tsu-Nai Wang, Po-Lin Kuo, Hui-Min David Wang, Eing-Mei Tsai*, Chien-Chih Chiu*. The impact of Bis(2-ethylhexyl) phthalate (DEHP) on cancer progression. Archivum Immunologiae et Therapiae Experimentalis. 2017 66.3: 183-197.

21.      WT Chang, W Liu, YH Chiu, BH Chen, SC Chuang, YC Chen, YT Hsu, MJ Lu, SJ Chiou, CK Chou, and Chien-Chih Chiu*. A 4-Phenoxyphenol Derivative Exerts Inhibitory Effects on Human Hepatocellular Carcinoma Cells through Regulating Autophagy and Apoptosis Accompanied by Downregulating α-Tubulin Expression. Molecules, 2017, 22,854. 

22.      Chang WT, Fong Y, Chuang SC, Chou CK, Chou HL, Yang CF, Tseng CH, Chen YL,Chien-Chih Chiu*. 9-bis[2-(pyrrolidin-1-yl) ethoxy] -6-{4-[2-(pyrrolidin-1-yl) ethoxy]phenyl}-11H-indeno [1,2-c]quinolin-11-one (BPIQ), a quinoline derivative inhibits human hepatocellular carcinoma cells by inducing ER stress and apoptosis. Anticancer Agents Med Chem.2017;17(5):692-700. 

23.      Wen-Tsan Chang, Wangta Liu, Yi-Han Chiu, Bing-Hung Chen, Shih-Chang Chuang, Yen-Chun Chen, Yun-Tzh Hsu, Mei-Jei Lu, Shean-Jaw Chiou, Chon-Kit Chou, and Chien-Chih Chiu*. A 4-Phenoxyphenol Derivative Exerts Inhibitory Effects on Human Hepatocellular Carcinoma Cells through Regulating Autophagy and Apoptosis Accompanied by Downregulating α-Tubulin Expression. Molecules. 2017 May 21;22(5)

24.      Chon-Kit Chou, Chin-Ju Tang, Han-Lin Chou, Chun-Yen Liu, Ming-Chong Ng, Yu-Ting Chang, Shyng-Shiou F. Yuan, Eing-Mei Tsai, Chien-Chih Chiu*. The Potential Role of Krüppel-Like Zinc Finger Protein Glis3 in Genetic Diseases and Cancers. Arch Immunol Ther Exp (Warsz). 2017 May 18

25.      Fong Y, Wu CY, Chang KF, Chen BH, Chou WJ, Tseng CH, Chen YC, Wang HD, Chen YL, Chien-Chih Chiu*. Dual roles of the extracellular signal-regulated kinase (ERK) in quinoline compound BPIQ-induced apoptosis and anti-migration of human non-small cell lung cancer cells. Cancer Cell Int. 2017 Mar 7;17:37.

26.      Chon-Kit Chou, Yu-Ting Chang, Michal Korinek, Yei-Tsung Chen, Ya-Ting Yang, Steve Leu, I-Ling Lin, Chin-Ju Tang, Chien-Chih Chiu*. The regulations of deubiquitinase USP15 and its pathophysiological mechanisms in diseases. Int J Mol Sci. 2017 Feb 24;18(3) 

27.      Chou HL, Fong Y, Lin HH, Tsai EM, Chen YF, Chang WT, Wu CY, Wang HM, Huang HW, and  Chien-Chih Chiu * An acetamide derivative as a camptothecin sensitizer for human non-small cell lung cancer cells through increased oxidative stress and JNK activation". Oxid Med Cell Longev. 2016. Article ID 9128102. 

28.      Fong Y, Tang CC, Hu HT, Fang HY, Wu CY, Yuan SS, Wang HM, Chen YC, Teng YN, and Chien-Chih Chiu *. The inhibitory effect of trans-Ferulic acid on proliferation and migration of human lung cancer cells through modulating endogenous ROS and beta-catenin activity. Chinese Medicine, 2016 11:45. eCollection 2016. 

29.      Liu YS, Cheng RY, Lo YL, Hsu C, Chen SH, Chien-Chih Chiu*, Wang LF*. (*Corresponding authors) (2016, Jan). Distinct CPT-induced deaths in lung cancer cells caused by clathrin-mediated internalization of CP micelles. Nanoscale, 8(6):3510-22. 

30.      Chien-Chih Chiu*, Kuo-Feng Chang, Bing-Hung Chen, Han-Lin Chou, Chih-Hua Tseng, Yao Fong, Tzu-Fun Fu, Hsueh-Wei Chang, Chang-Yi Wu, Eing-Mei Tsai, Shinne-Ren Lin and Yeh-Long Chen* (*Corresponding authors) (2015, Dec). BPIQ, a novel synthetic quinoline derivative, inhibits growth and induces mitochondrial apoptosis of lung cancer cells in vitro and in zebrafish xenograft model. BMC Cancer, 15:962. 

31.      Chih-Hua Tseng, You-Ren Chen, Cherng-Chyi Tzeng, Wangta Liu, Chon-Kit Chou, Chien-Chih Chiu*, Yeh-Long Chen* (*Corresponding authors) (2015, Nov). Discovery of Indeno[1,2-b]quinoxaline Derivatives as Potential Anticancer Agents. European Journal of Medicinal Chemistry. 

32.      Kai-Chun Cheng, Chun-Tzu Hung, Kuo-Jen Chen, Wen-Chuan Wu, Jau-Ling Suen, Cheng-Hsien Chang, Chi-Yu Lu, Chih-Hua Tseng, Yeh-Long Chen, Chien-Chih Chiu* (2015, Aug). Quinoline-Based Compound BPIQ Exerts Anti-Proliferative Effects on Human Retinoblastoma Cells via Modulating Intracellular Reactive Oxygen Species. Arch Immunol Ther Exp (Warsz). 2015 Apr;64(2):139-47 

33.      Chon-Kit Chou, Chang-Yi Wu, Jeff Yi-Fu Chen, Ming‐Chong Ng, Hui-Min David Wang, Jen-Hao Chen, Shyng-Shiou F Yuan, Eing-Mei Tsai, Jan-Gowth Chang*, Chien-Chih Chiu* (2015, Jul). BubR1 Acts as a Promoter in Cellular Motility of Human Oral Squamous Cancer Cells through Regulating MMP-2 and MMP-9. International Journal of Molecular Sciences, 16(7):15104-17.

Conferences 

·   Han-Lin Chou, Hurng-Wern Huang, Chien-Chih Chiu*. Chloroquine synergistically promotes C2-ceramide-induced apoptosis of non-small cell lung cancer cells via inhibiting sirt1 expression. 2013 Taiwan Zebrafish Symposium Dec. 7. Institute of Biomedical Sciences Academia Sinica. #P22. (The best poster award).  台灣斑馬魚研討會

·      Mei-Jei Lu and Chien-Chih Chiu*. The effect of Akt-targeting compounds on proliferation and apoptosis of lung cancer cells in zebrafish xenografts.2013 Taiwan Zebrafish Symposium Dec. 7. Institute of Biomedical Sciences Academia Sinica.#P23. 台灣斑馬魚研討會

·      Chien Chih, Chiu, and  Bing-Hung Chen*. Anti-allergic activity of grape seed extract (GSE) on RBL-2H3 mast cells. The 19th Symposium of Young Asian Biochemical Engineer’s Community (YABEC). (ORAL#1). 2013. Urumqi, China.

·       Chon Kit, Chou, Chien Chih, Chiu*. The 19th Symposium of Young Asian Biochemical Engineer’s Community (YABEC). (POSTER#PD1). YABEC 2013. Urumqi, China. (YABEC *best poster award)
·       Han Lin, Chou, Chien Chih, Chiu*. The 19th Symposium of Young Asian Biochemical Engineer’s Community (YABEC). (POSTER#PD2). 2013. Urumqi, China. 

·       Yin-Chieh Lin, Jeff Yi-Fu Chen, Chien-Chih Chiu*. The inhibitory effects of sirtinol, a sirtuin inhibitor on invasion of non-small cell lung cancer cells via Src signaling. The 18th Symposium of Young Asian Biochemical Engineer’s Community (YABEC) 2012. (ORAL: O-CD-7).

·       Pin-Hsuan Wu, Jeff Yi-Fu Chen, Yeh-Long Chen, Chien-Chih Chiu*. Naphtho[1,2-b] furan-4,5-dione, a naphthoquinone derivative induces anti-cell growth and anti-migration in non-small cell lung cancer by inhibiting topoisomerase II. Bio-IT WORLD ASIA in Marina Bay Sands Hotel, Singapore, in June 6-8, 2012. (*corresponding). (POSTER #6) Session of Drug Discovery and Bioinformatics.

·       Yuli C. Chang, Shih-Ya Hung, Chien-Chih Chiu, Wen-Lin Chan, Wen-Hsin Chang, Shou-Mei Wu, Ya-Sian Chang, Chung-Yee Yuo, Ta-Chih Liu, Wen-Kuang Yang, Jan-Gowth Chang*. Participation of an XIST-related small RNA in the formation of the K-RAS G-quadruplex. Non-Coding RNAs (Z1) Keystone Symposia conference. Snowbird, Utah, USA, in March 31-April 5. 2012

·       Yin-Chieh Lin, Han-Lin Chou, Chien-Chih Chiu＊. The inhibitory effects of sirtuin1 inhibitor, sirtinol on migration and anchorage-independent growth of lung cancer cells. (POSTER #85) SCMB2012. 第20 屆細胞及分子生物新知研討會 (*corresponding)

·       Han-Lin Chou, Feng-Wei Chen, Xin-Ping Tang, Hurng-Wern Huang＊, Chiu, Chien-Chih＊. The synergistic effect of C2-ceramide in Doxorubicin was induced senescence of non-small-cell lung cancer (NSCLC). (POSTER #57) SCMB2012. 第20 屆細胞及分子生物新知研討會 (*corresponding)

·       Chon Kit Chou, Han-Lin Chou, Feng-Wei Chen, Chien-Chih Chiu*.The Novel Function of BubR1 in Migration Ability of Non-Small Cell Lung Cancer Cells. (POSTER #121) SCMB2012. 第20 屆細胞及分子生物新知研討會(*corresponding)

·       Huei-Ting Hu, Hsueh-Wei Chang*, Lian-Je Hwang, Hsin-Yu Fang, Chien-Chih Chiu*. Effect of ferulic acid on anti-oxidation and cell proliferation of human lung cancer cells. (POSTER #95) SCMB 2012. 第20 屆細胞及分子生物新知研討會. (*corresponding)

·       Pin-Hsuan Wu, Chien-Chih Chiu*, Yeh-Long Chen, Hsueh-Wei Chang. A novel naphthoquinone derivative-induced apoptosis and growth inhibition of human non-small cell lung cancer (NSCLC). (POSTER #27) SCMB2012. 第20 屆細胞及分子生物新知研討會. (*corresponding)

·       Chiu-Chien Chiu*, Chon-Kit Chou, Han-Lin Chou. Goniothalamin inhibits the growth of human lung cancer cells through DNA damage, apoptosis, and reduced migration ability. (Oral and POSTER) (POSTER # F14). The 17th Symposium of Young Asian Biochemical Engineer’s Community (YABEC) in Incheon, Korea on Oct 7-9,2011. (*corresponding)

·       Kuo-Feng Chang, Hsueh-Wei Chang, Tso-Wen Wang, Chih-Hua Tseng, Yeh-Long Chen, Chien-Chih Chiu*. The mechanistic study of quinoline-derivative-induced apoptosis and growth inhibition of lung cancer. (POSTER #160) SCMB 2011. 第19屆細胞及分子生物新知研討會. (*corresponding)

·       Kuo-Feng Chang, Hsueh-Wei Chang, Wan-Ju Chou, Chih-Hua Tseng, Yeh-Long Chen, Chien-Chih Chiu*. The quinoline-derivative DFIQ induced apoptosis and growth inhibition of lung cancer. SCMB 2011. 第19屆細胞及分子生物新知研討會. (*corresponding)

·       Han-Lin Chou, Hsueh-Wei Chang, Pi-Chuan Hsieh, Xin-Ping Tang, Feng-Wei Chen, Hurng-Wern Huang*, Chiu, Chien-Chih*. Role of exogenous ceramides in modulating the expression of human type III deacetylase SIRT-1 and SIRT-2 of human non-small cell lung cancer (NSCLC) cells. (POSTER #86) SCMB 2011.第19屆細胞及分子生物新知研討會. (*corresponding)

·       Yin-Chieh Lin, Jeff Yi-Fu Chen, Hsueh-Wei Chang*, Chien-Chih Chiu*. The modulation of cell proliferation induced by exogenous ceramide in human breast cancer cells. (POSTER #114) SCMB 2011. 第19屆細胞及分子生物新知研討會. (*corresponding)

·       Huei-Ting Hu, Hsueh-Wei Chang, Lian-Je Hwang, Hsin-Yu Fang, Chien-Chih Chiu*. Effect of feruloyl xylooligosaccharides on antioxidant activity and cell migration in human lung cancer H1299 cells. (POSTER #133) SCMB 2011. 第19屆細胞及分子生物新知研討會. (*corresponding)

·       Pin-Hsuan Wu, Chien-Chih Chiu*, Yeh-Long Chen, and Hsueh-Wei Chang*. NFD inhibits cell proliferation and migration of human non-small cell lung cancer (NSCLC) cell through DNA damage and reduced migration ability. (POSTER #50) SCMB 2011. 第19 屆細胞及分子生物新知研討會. (*corresponding)

·       Chon-kit Chou, Han-Lin Chou, Pin-Hsuan Wu, Hsueh-Wei Chang* and Chien-Chih Chiu*. The effect of spindle assembly checkpoint kinase BubR1 on cellular migration in oral squamous cell carcinoma. (POSTER #171) SCMB 2011. 第19 屆細胞及分子生物新知研討會. (*corresponding)

·       Kuang-Jing Huang, Chien-Chih Chiu*, Fang-Rong Chang, Yang-Chang Wu, Hsueh-Wei Chang*. AN10 is a potential natural product-derived drug against oral cancer. SCMB 2011. 第19 屆細胞及分子生物新知研討會.(*corresponding)

·       Kuang-Jing Huang, Chien-Chih Chiu*, Fang-Rong Chang, Yang-Chang Wu, Hsueh-Wei Chang*. AN10 inhibits the growth of human lung cancer cells through DNA damage, apoptosis, and reduced migration ability. (POSTER #256) SCMB 2011. 第19屆細胞及分子生物新知研討會. (*corresponding)

·       Kuang-Jing Huang, Chien-Chih Chiu*, Fang-Rong Chang, Yang-Chang Wu, Hsueh-Wei Chang*. SCMB 2011. AN37 is a potential natural product-derived drug against oral cancer.第19屆細胞及分子生物新知研討會.

·       Jeff Yi-Fu Chen, Chien-Chih Chiu, Yu-Jen Wu, Hau-Ren Chen. Betel Quid Extract Promotes Oral Cancer Cell Migration by Activating a Muscarinic M4 Receptor-Mediated Signaling Cascade Involving ERK1/2 and SFKs. 4th World Congress of International Federation of Head and Neck Oncologic Societies in Seoul, Korea on June 15-19, 2010.

·       Guang-Jing Huang, Ming-Tz Tsai, Chon-Kit Chou, Chien-Chih Chiu, Yang-Chang Wu, Hsueh-Wei Chang. Growth inhibition of lung cancer cell using herb-derived compound AN10 based on cell migration analysisSCMB 2010. 第18屆分子生物學會冬令營

·       Yung-Lan Su, Yi-Han Lo, Wan-Yu Chen, Tsung-Lun Kuo, Jan-Gowth Chang*, Chien-Chih Chiu*.Characterization of ectopic expression of nuclear export factor (NXF) in human hepatoma cells Huh-7 (POSTER # P331) The Twenty-fourth Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan. (Mar. 21-22, 2009). 第24屆生物醫學聯合學術年會 (*corresponding)

·       Chien-Chih Chiu* (Oral Presentation # O46 ). Effects of ectopically expressed nuclear export factor (NXF) on cell migration and adhesion in human hepatoma cells. The Twenty-fourth Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, Mar. 21-22, 2009. 第24屆生物醫學聯合學術年會 (*oral and corresponding)

·       Pi-Chuan Hsieh, Chien-Chih, Chiu, Jan-Gowth Chang, Sheng-Fung Lin.BubR1 Gene Is Involved in Ceramide Induced Mitotic Arrest in Malignant Cancer Cells. (May 2007). 第12屆台灣癌症聯合學術年會

·       Ying-Chieh Chu, Kai-Li Su, Min-Tsui Wu, Chien-Chih Chiu*. The effects of caffeic acid in anticancer drug-induced human non-small cell lung cancer (NSCLC) cells. (Mar 2007). 第22屆生物醫學年會 (*corresponding)