聯絡方式:

  • 辦公室第一教學大樓N1035
  • 實驗室第一教學大樓N1028
  • 電話: (07) 3121101 ext. 2790
  • 傳真: (07) 3125339
  • 電子郵件liuwangta@kmu.edu.tw


 

學經歷:

  • 逢甲大學環境工程與科學學系學士(1997)
  • 國立中山大學海洋生物科技暨資源學系碩士(1999)
  • 國立中山大學海洋生物科技暨資源學系博士(2006)
  • 中央研究院細胞與個體生物學研究所博士後研究員(2006-2011)
  • 中央研究院基因體研究中心博士後研究員(2011-2013)
  • 高雄醫學大學生物科技學系助理教授(2013/08-至今)

 

主負責授課科目:

  • 水生動物基因轉殖及應用
  • 模式生物學
  • 3D列印在生物醫學上的應用
  • 斑馬魚藥物篩選平台的建立與實作

 

研究興趣:

 LHDMZ

實驗室團照01 m          

 

實驗室成員:

     

  

 

 

近期研究成果:

  • Li, Y. H., Chen, H. Y., Li, Y. W., Wu, S. Y., Liu, W., Lin, G. H., Hu, S. Y., Chang, Z. K., Gong, H. Y., Liao, C. H., Chiang, K. Y., Huang, C. W. and Wu, J. L. (2013) Progranulin regulates zebrafish muscle growth and regeneration through maintaining the pool of myogenic progenitor cells. Scientific Reports 3, 1176.
  • Liu, W., Chen, J. R., Hsu, C. H., Li, Y. H., Chen, Y. M., Lin, C. Y., Huang, S. J., Chang, Z. K., Chen, Y. C., Lin, C. H., Gong, H. Y., Lin, C. C., Kawakami, K., Wu, J. L. (2012). A zebrafish model of intrahepatic cholangiocarcinoma by dual expression of hepatitis B virus X and hepatitis C virus core protein in liver. Hepatology 56, 2268-2276.
  • Wang, W. L., Liu, W., Gong, H. Y., Hong, J. R., Lin, C. C. and Wu, J. L. (2011). Activation of cytokine expression occurs through the TNFα/NF-κB-mediated pathway in birnavirus-infected cells. Fish and Shellfish Immunology 31, 10-21.
  • Wang, W. L., Hong, J. R., Lin, G. H., Liu, W., Gong, H. Y., Lu, M. W., Lin, C. C. and Wu, J. L. (2011). Stage-specific expression of TNFα regulates bad/bid-mediated apoptosis and RIP1/ROS-mediated secondary necrosis in Birnavirus-infected fish cells. PLoS One 6, e16740.
  • Li, Y. H., Chen, M. H., Gong, H. Y., Hu, S. Y., Li, Y. W., Lin, G. H., Lin, C. C., Liu, W. and Wu, J. L. (2010). Progranulin A-mediated MET signaling is essential for liver morphogenesis in zebrafish. The Journal of Biological Chemistry 285, 41001-41009.
  • Wu, Y. M., Hsu, C. H., Wang, C. H., Liu, W., Chang, W. H., Lin, C. S. (2008). Role of the DxxDxD motif in the assembly and stability of betanodavirus particles. Archives of Virology 153, 1633-1642.
  • Liu, W., Hsu, C. H., Chang, C. Y. Chen, H. H. Lin, C. S. (2006). Immune response against grouper nervous necrosis virus by vaccination of virus-like particles. Vaccine 24, 6282–6287.
  • Liu, W., Hsu, C. H., Hong, Y. R., Wu, S. C., Wang, C. H., Wu, Y. M., Chao, C. B. and Lin, C. S. (2005). Early Endocytosis Pathways in SSN-1 Cells Infected by Dragon Grouper Nervous Necrosis Virus. Journal of General Virology. 86, 2553–2561.
  • Lu, M. W., Liu, W. and Lin. C. S. (2003). Infection competition against grouper nervous necrosis virus by virus-like particles produced in Escherichia coli. Journal of General Virology. 84, 1577-1582.
  • Lin, C. S., Lu, M. W., Tang, L., Liu, W., Chao, C. B., Lin, C. J., Krishna, N. K., Johnson, J. E. and Schneemann, A. (2001). Characterization of virus-like-particles assembled in a recombinant baculovirus system expressing the capsid protein of a fish nodavirus. Virology 290, 50-58.

 

 

研討會論文:

  • Wangta Liu, Chi-Hsueh Lin, Chih-Hao Hsu, Shin-Jie Huang, Yen-Hsing Li, Hong-Yi Gong and Jen-Leih Wu. Initiation mechanism of intrahepatic cholangiocarcinoma formation in zebrafish. The 8th European Zebrafish Meeting. Barcelona, Spain. July 9-13, 2013.
  • Chi-Hsueh Lin, Wangta Liu, Jim-Ray Chen, Chih-Hao Hsu, Yi-Meng Chen, Chien-Yuan Lin, Shin-Jie Huang, Hong-Yi Gong, Yen-Hsing Li, Ching-Chun Lin, Zen-Kuei Chang, Yan-Chun Chen, Koichi Kawakami, Jen-Leih Wu. The role of TGF-β1/pSmad3L oncogenic pathway in the initiation of ICC formation in zebrafish. The 28th Joint Annual Conference of Biomedical Science. Taipei, Taiwan. March 3~4. 2013. P352.
  • Liu, W., Chen, J. R., Li, Y. S., Gong, H. Y., Kawakami, K. and Wu, J. L. (2012) Involvement of TGF-β1 in intrahepatic cholangiocarcinoma formation using HBx and HCV core dual transgenic zebrafish as a model. Fishing for Answers: Zebrafish Models of Human Development and Disease, 2012 Cold Spring Harbor Asia Conference, Suzhou, China. April 16~20, 2012. p44.
  • Lin, C. H., Liu, W., Chen, J. R., Hsu, C. H., Chen, Y. M., Lin, C. Y., Huang, S. J., Gong, H. Y., Li, Y. H., Lin, C. C., Chang, Z. K., Chen, Y. C., Kawakami, K. and Wu, J. L. Global gene expression profile of ICC using next generation sequencing. The 27th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, March 17-18, 2012. p955.
  • Chen, H. Y., Chen, Y. C., Liu, W. and Wu, J. L. The retinoic acid-inducible gene I plays a major role in interferon induction during NNV infection. The 27th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan. March 17-18, 2012. p806.
  • Li, Y. H., Li, Y. W., Liu, W. and Wu, J. L. Progranulin is required for postnatal muscle hypertrophy and proliferation of satellite cells in zebrafish. 7th European Zebrafish Meeting, Edinburgh, Scotland, July 5-9, 2011. P1-71.
  • Li, Y. H., Liu, W., Li, Y.W. and Wu, J.L. Regulatory Mechanism of Progranulin in Liver Organogenesis in Zebrafish. 7th European Zebrafish Meeting. Edinburgh, Scotland, July 5-9, 2011. P2-26,
  • Li, Y. H., Chen, H. C., Gong, H. Y., Hu. S. Y., Li, Y. W., Lin, G. H., Lin, C. C., Liu, W. and Wu, J. L. Progranulin A-mediated met signaling is essential for liver morphogenesis in zebrafish. 44th Annual Meeting of Japan Society of Developmental Biologists, Okinawa, May 18-21, 2011. p-2101.
  • Hsu, C. H., Liu, W., Chen, J. R., Chen, Y. M., Lin, C. Y., Huang, S. J., Gong, H. Y., Li, S. H., Lin, C. C., Kawakami, K. and Wu, J. L. Generation of ICC model by co-expression of HCV core and HBV X in zebrafish liver.The 26th Joint Annual Conference of Biomedical Science, Taipei, Taiwan. March 19-20, 2011. p789.
  • Chen, H. Y., Chen, Y. C., Liu, W., Hong, J. R. and Wu, J. L. (2011) The stage specific interferon expression between NNV infected zebrafish. The 26th Joint Annual Conference of Biomedical Science, Taipei, Taiwan. March 19-20, 2011. p536.
  • Huang, C. W., Hu, S. Y., Li, Y. H., Chi, J. R., Gong, H. Y., Liu, W., Wang, W. L., Lin, G. H., Chen, R. H., Chang, S. J., Liu, J. G. and Wu, J. L. Analysis of microRNA transcriptome by deep sequencing of skeletal muscle in Nile Tilapia (Oreochromis niloticus). The 26th Joint Annual Conference of Biomedical Science, Taipei, Taiwan. March 19-20, 2011. p531.
  • Li, Y. H., Liu, W., Lee, Y. W. and Wu, J. L. Regulatory mechanism of Progranulin A in liver morphogenesis in zebrafish. The 26th Joint Annual Conference of Biomedical Science, Taipei, Taiwan. March 19-20, 2011. p484.
  • Wang, W. L., Liu, W., Gong, H. Y., Hong, J. R., Lin, C. C. and Wu, J. L. Activation of cytokines expression occurs through the TNFα/NF-κB-mediated pathway in birnavirus infected cells.The 26th Joint Annual Conference of Biomedical Science, Taipei, Taiwan. March 19-20, 2011. p242.
  • Wang, W. L., Hong, J. R., Lin, G. H., Liu, W., Gong, H. Y., Lu, M. W., Wu, J. L. (2011) Expression of TNFα regulates Bad/Bid and RIP1/ROS-mediated cell death in birnavirus-infected fish cells. The 26th Joint Annual Conference of Biomedical Science, Taipei, Taiwan. March 19-20, 2011. p241.
  • Huang, C. C., Chang, Z. K., Chen, J. R., Lin, M. Y., Li, Y. H., Liu, W., Lin, G. H., Lin, C. C., Gong, H. Y. and Wu, J. L. Initiation mechanism of intrahepatic cholangiocarcinoma progression in liver-specific IMP2 transgenic zebrafish. The 26th Joint Annual Conference of Biomedical Science, Taipei, Taiwan. March 19-20, 2011. p74.
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