Lin YT

聯絡方式:


學經歷:

  • 國立交通大學 應用化學系 學士 (1994)
  • 國立中正大學 化學與生物化學所 碩士 (1996)
  • 國立中正大學 化學與生物化學所 哲學博士 (2000) 
  • 國家衛生研究院 生物技術與藥物研究組 博士後研究員 (2001-2004)
  • 國家衛生研究院 生物統計與生物資訊研究組 研究專員 (2005)
  • 高雄醫學大學 生物科技學系 助理教授 (2006-2012)
  • 高雄醫學大學 生物科技學系 副教授 (2013 - Present)


主負責授課科目:

  • 生物資訊學
  • 嵌合演算法
  • 電腦輔助藥物設計
  • 計算生物醫藥科學特論
  • 電腦在生物醫藥上的應用


研究興趣:

  • 化學資訊學
  • 計算醫藥化學
  • 計算生物化學
  • 電腦藥物篩選
  • 結構生物資訊學

 

期刊論文: (8 selected)

  • Ying-Ting Lin*, "A tandem regression-outlier analysis of a ligand cellular system for key structural modifications around ligand binding" Journal of Cheminformatics, (2013), 5:21. (SCI/IF=3.590; computer science, information systems, Rank=Q1, 7/132 (5.3%); computer science, interdisciplinary applications, Rank=Q1, 6/99 (6.1%) in JCR 2012 version)  (SCI/IF=4.540; computer science, information systems, Rank=Q1, 5/135 (3.7%); computer science, interdisciplinary applications, Rank=Q1, 4/102 (3.9%) in JCR 2013 version) (5-Year IF= 4.797 in JCR 2013 version)
  • Huang-Kai Peng, Wei-Chun Chen, Jin-Ching Lee, Cherng-Chyi Tzeng, Ying-Ting Lin,* and Shyh-Chyun Yang*, "Novel anilinocoumarin derivatives as agents against hepatitis C virus by the induction of IFN-mediated antiviral responses", Organic & Biomolecular Chemistry (2013), 11, 1858. (SCI/IF=3.568; chemistry, organic, Rank=Q1, 11/55 (20%) in JCR 2012 version)
  • Ying-Ting Lin (co-first authors), Yu-Hsiang Lo, Ying-Ting Lin, Yu-Peng Liu, Tsai-Hui Duh, Pei-Jung Lu and Ming-Jung Wu*, "Design, Synthesis, Biological Evaluation and Molecular Modeling Studies of 1-Aryl-6-(3,4,5-trimethoxyphenyl)-3(Z)-hexen-1,5-diynes as a New Class of Potent Antitumor Agents", European Journal of Medicinal Chemistry (2013), 61, 526-533. (SCI/IF=3.499; chemistry, medicinal, Rank=Q1, 13/59 (22.0 %) in JCR 2012 version)
  • Ying-Ting Lin, Yu-Hsuan Wu, Chin-Kai Tseng, Chun-Kuang Lin, Wei-Chun Chen,Yao-Chin Hsu, and Jin-Ching Lee, "Green tea phenolic epicatechins inhibit hepatitis C virus replication via cycloxygenase-2 and attenuate virus-induced inflammation", PloS One (2013), 8 (1), e54466. (SCI/IF=3.730; multidisciplinary sciences, Rank=Q1, 7/56 (12.5%) in JCR 2012 version)
  • Ying-Ting Lin* and Guan-Yu Chen, "A Scaffold-Independent Subcellular Event-Based Analysis: Characterization of Significant Structural Modifications." Journal of Chemical Information and Modeling, (2012), 52(2), 506-514. (SCI/IF=4.675; computer science, information systems, Rank=Q1, 2/135 (1.5%); computer science, interdisciplinary applications, Rank=Q1, 1/99 (1.0%) in JCR 2011 version)
  • Ying-Ting Lin (co-first authors), Chia-Lin Lee, Fang-Rong Chang, Guan-Yu Chen, Anders Backlund, Juan-Chang Yang, Shu-Li Chen,and Yang-Chang Wu*, "Synthesis and Biological Evaluation of Phenanthrenes as Cytotoxic Agents with Pharmacophore Modeling and ChemGPS-NP Prediction as Topo II Inhibitors", Plos One (2012), 7(5), e37897. (SCI/IF=4.092; biology, Rank=Q1, 12/84 (14.3%) in JCR 2011 version)
  • Ying-Ting Lin*, Kuo-Jung Huang, Chin-kai Tseng, Kuan-Jen Chen, Hui-Min Wang, and Jin-Ching Lee, "Efficient In Silico Assay of Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase by Structure-Based Virtual Screening and In Vitro Evaluation." Assay and Drug Development Technologies, (2011) 9, 290-298. (SCI/IF=2.731; biochemical research methods, Rank=Q2, 25/67(37.3%); pharmacology & pharmacy, Rank=Q2, 95/252 (37.7%) in JCR 2010 version)
  • Jin-Ching Lee, Chin-kai Tseng, Kuan-Jen Chen, Kuo-Jung Huang, Chun-Kuang Lin, Ying-Ting Lin*, "A Cell-based Reporter Assay for inhibitor screening of Hepatitis C Virus RNA dependant RNA Polymerase." Analytical Biochemistry, (2010) 403, 52-62. (SCI/IF=3.287; chemistry, analytical, Rank=Q1, 10/70 (14.3 %) in JCR 2009 version)

 

研討會論文: (1 selected)

  • Lee, Jia-Hau, Chuang, Yi-Jing, Lin, Ying-Ting*, "Explore the molecular-descriptor-drug-action relationship inside ligand cellular system of nuclear receptor", Acta pharmacologica sinica (2013) 34, 44. (The 12th meeting of the Asia Pacific Federation of Pharmacologists (APFP), sponsored by Chinese Pharmacological Society (CNPHARS), held in Shanghai, China.)
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