聯絡方式:

• 研究室: N1022, 第一教學大樓
• 實驗室: N1020,第一教學大樓
• 電話: +886-7-3121101 ext. 2368
• 傳真: +886-7-3125339
• E-mail: cchiu@kmu.edu.tw
• Researchgate: https://www.researchgate.net/profile/Chien_Chih_Chiu/
• ORCID: http://orcid.org/0000-0001-7307-2468

學經歷:

• 中山大學生物系理學士 (1996)
• 中山大學生物科學系碩士 (1998)
• 臺灣師範大學生命科學系理學博士 (2004)
• 臺灣師範大學生命科學系 博士後研究員 (2004-2005)
• 高雄師範大學生物科技學系 兼任助理教授 (2006)
• 高雄醫學大學生物科技學系 助理教授 (2005-2011)
• 高雄醫學大學附設中和醫院 轉譯醫學研究中心 副研究員 (2014)
• 高雄醫學大學生物科技學系 副教授 (2011.08 - 2014.08)
• 高雄醫學大學生物科技學系 教授 (2014.09 - Presen)
• 高雄醫學大學醫學研究所 合聘教授 (2016.08 - Present)
• 中山大學生物科學系 合聘教授 ( 2016.08- Present) 

主負責授課科目：

• 基因體學與蛋白質體學
• 腫瘤生物學
• 書報討論 

講義下載：

• 大學部課程

普通生物學
普通生物學實驗
服務學習
電腦生物
分子生物學
自由基生物學
基因體及蛋白質體學
腫瘤生物學

• 研究所課程

腫瘤生物學特論
細胞生物學特論
生命科學特論

 研究興趣:

• 抗癌藥物篩選與機制探討
• mRNA輸出調節與腫瘤相關基因表現機制
• 斑馬魚模型在藥物篩選的應用

 ＠＠　招募實驗室生力軍！　歡迎積極有耐心、願意學習的同學加入我們！（不限科系、大學部或研究生皆可）

期刊論文: (連結科技部) [C302 下載]

• I-Ling Lin, Han-Lin Chou, Jin-Ching Lee, Feng-Wei Chen, Yao Fong, Wei-Chiao Chang, H.-W. Huang, Chang-Yi Wu, Wen-Tsan Chang, Chien-Chih, Chiu*. The antiproliferative effect of C2-ceramide on lung cancer cells through apoptosis by inhibiting Akt and NFκB. “Cancer cell international . 2014 Jan. 14:1.
• Chao-Neng Tseng, Chung-Lung Cho, Tzan-Wen Chen, Chien-Chih Chiu, Hsueh-Wei Chang, Fang-Rong Chang, Yung-Fu Chang. Brefeldin A inhibits Cancer Stem Cell Properties in Human Lung Cancer Cells. Current Signal Transduction Therapy. 2013. Aug 113-118 (6).
• Tsai JR, Chong IW, Chen YH, Hwang JJ, Yin WH, Chen HL, Chou SH, Chien-Chih Chiu, Liu PL.. Magnolol induces apoptosis via caspase-independent pathways in non-small cell lung cancer cells. Archives of pharmacal research, 1-10. 2013.  PMID: 23943503 
• Jing-Ping Wang, Kai-Han Lin, Chun-Yen Liu, Ya-Chu Yu, Chien-Chih Chiu, Chun-Li Su, Kwun-Min Chen, Kang Fang. Teroxirone inhibited growth of human non-small cell lung cancer cells by activating p53" Toxicology and Applied Pharmacology. 2013. 273(1):110-120. PMID: 23954467
• Pei-Chien Tsai, Chiao-Lun Chu, Chien-Chih Chiu, Long-Sen Chang, Shinne-Ren Lin. Inhibition of Src activation with Cardiotoxin III blocks migration and invasion of MDA-MB-231 cells. Toxicon. 2013. 74, 56-67.  
• Chao-Neng Tseng, Chien-Fu Huang, Chung-Lung Cho, Hsueh-Wei Chang, Chao-Wei Huang, Chien-Chih Chiu*, and Yung-Fu Chang*. Brefeldin A Effectively Inhibits Cancer Stem Cell Properties and MMP-9 Activity in Human Colorectal Cancer Colo 205 cells. “Molecules”. 2013  18, 10242-10253
• Hsing-Hui Li, Jui-Hsin Su Su@, Chien-Chih, Chiu@, Jen-Jie Lin, Zih-Yan Yang, Wen-Ing Hwang, Yu-Kuei Chen, Yu-Hsuan Lo, Yu-Jen Wu*. Proteomic investigation of the sinulariolide-treated melanoma cells A375: effects on the cell apoptosis through mitochondrial-related pathway and activation of caspase cascade (@ contributed equally). ”Marine Drugs”. 2013, 11(7), 2625-2642; IF:3.978.
• Chien-Chih Chiu, Jo-Wen Huang, Fang-Rong Chang, Kuang-Jing Huang, Hsuan-Min Huang, Hurng-Wern Huang, Chon-Kit Chou, Yang-Chang Wu, Hsueh-Wei Chang*. Golden berry-derived 4β-hydroxywithanolide E for selectively killing oral cancer cells by generating ROS, DNA damage, and apoptotic pathways. PLoS ONE. 2013; 8(5): e64739.
• Hsin-Yu Fang, Hui-Min Wang, Kuo-Feng Chang, Huei-Ting Hu, Lian-Je Hwang, Tzu-Fun Fu, Yin-Chieh Lin, Wei-Chiao Chang, Tsu-Pei Chiu, Zhi-Hong Wen , Chien-Chih Chiu*, Bing-Hung Chen* Feruloyl-L-arabinose attenuates migration, invasion and production of reactive oxygen species in H1299 lung cancer cells. Food and Chemical Toxicology.2013. 58:496-466.
• Ching-Yu Yen, Shih-Shin Liang, Lo-Yi Han, Han-Lin Chou, Chon-Kit Chou, Shinne-Ren Lin*, Chien-Chih Chiu*. The Scientific World Journal. 2013. e650946. IF:1.73.
• Chih-Chen Lee, Chien-Chih Chiu, Wei-Ting Liao, Pei-Fang Wu, Yi-Ting Chou, Kuo-Chuan Huang, Yen-Ting Chen, Zhi-Hong Wen and Hui-Min Wang*. Alpinia oxyphylla Miq. bioactive extracts from supercritical fluid carbon dioxide extraction. Biochemical Engineering Journal. 2013. 
• Joel Stocker, Hurng-Wern Huang, Hong-Ming Wang, Hsueh-Wei Chang, Chien-Chih Chiu, Chung-Lung Cho, and Chao-Neng Tseng. Reduction of RNA A-to-I editing in Drosophila acclimated to heat shock. “Kaohsiung Medical Science”. 2013. 29. 478-483. 
• Wen ling Chan, Chung Yee Yuo, Wen uang Yang, Shih Huang, Ya Ian Chang, Chien Chih Chiu, Kun Tu Yeh, Hsien Huang, Jan Jowth Chang. Transcribed pseudogene ψPPM1K generates endogenous  siRNA to suppress oncogenic cell growth in hepatocellular carcinoma. Nucleic Acid Research. 2013. 2013-02-26 (E-pub ahead)
• Yu-Lun Lo, Kuo-Hsun Sung, Chien-Chih Chiu and Li-Fang Wang. Chemically Conjugating Polyethylenimine with Chondroitin Sulfate to Promote CD44-Mediated Endocytosis for Gene Delivery. Molecular Pharmaceutics. 2013. 10:664-676.
• Wei-Fan Chiang, Tzer-Zen Hwang, Tzyh-Chyuan Hour, Lee-Hsin Wang, Chien-Chih Chiu, Hau-Ren Chen, Yu-Jen Wu, Chih-Chun Wang, Ling-Feng Wang, Chen-Yu Chien, Jen-Hao Chen, Chao-Tien Hsu, Jeff Yi-Fu Chen. Calreticulin, an endoplasmic reticulum-resident protein, is highly expressed and essential for cell proliferation and migration in oral squamous cell carcinoma. Oral Oncology. 2013. 49(6): 534-541.
• Wei-Chun Chen, Sheng-Yang Wang, Chien-Chih Chiu, Chin-Kai Tseng, Hui-Chun Wang, and Jin-Ching Lee. Lucidone Suppresses Hepatitis C Virus Replication by Nrf2-Mediated Heme Oxygenase-1 Induction.Antimicrobial Agents and Chemotherapy. 2013. 57(3): 1180-1191.
• Shih-Jer Huang, Shou-Li Sun, Chien-Chih Chiu, Li-Fang Wang. Retinol-encapsulated water-soluble succinated chitosan nanoparticles for antioxidant applications. Journal of Biomaterials Science, Polymer Edition2013. 24(3):315-329.
• Chih-Hua Tseng, Chi-Yi Li, Chien-Chih Chiu, Huei-Ting Hu, Chein-Hwa Han, Yeh-Long Chen, Cherng-Chyi Tzeng. Combretastatin A-4 derivatives: synthesis and evaluation of 2,4,5-triaryl-1H -imidazoles as potential agents against H1299 (non-small cell lung cancer cell). “Molecular Diversity”. 2012. 16:697-709.
• Yu-Ling Tsai, Chien-Chih Chiu, Jeff Yi-Fu Chen, Kung-Chi Chan, Sheng-Dun Lin. Cytotoxic effects of Echinacea purpurea flower extracts and cichoric acid on human colon cancer cells through induction of apoptosis. “Journal of Ethnopharmacology”. (IF: 2.32) 2012. 143(3): 914-919.
• Kim, S.H., Huang, C.Y., Tsai, C.Y., Lu, S.Y., Chien-Chih Chiu, Fang, K.. The aqueous extract of Prunella vulgaris suppresses cell invasion and migration in human liver cancer cells by attenuating matrix metalloproteinases. “The American journal of Chinese medicine” 2012. 40: 643-656.
• Pei-Chien Tsai, Chi-Ying Hsieh, Chien-Chih Chiu, Chih-Kuang Wang, Long-Sen Chang, Shinne-Ren Lin. CardiotoxinIIIsuppressesMDA-MB-231cellmetastasis through the inhibition of EGF/EGFR-mediated signaling pathway. “Toxicon”. 2012 60(5), 734-743.
• Yu Jen Wu *, Tzu-Rong Su, Feng-Jen Tsai, Jen-Jie Lin, Han Hsiang Huang, Chien-Chih Chiu, Jui-Hsin Su, Ya-ting Yang, Jeff Yi-fu Chen, Bing-sang Wong. Induction of apoptosis by 11-Dehydrosinulariolide via mitochondrial dysregulation and ER stress pathways in human melanoma cells. “Marine Drugs”. 2012, 10(80), 1883-1898.
• Ching-Yu Yen, Chien-Chih Chiu, Rou-Wen Haung, Chi-Chen Yeh, Kuang-Jing Huang, Kuo-Feng Chang, You-Cheng Hseu, Fang-Rong Chang, Hsueh-Wei Chang*, Yang-Chang Wu*. Antiproliferative effects of goniothalamin on Ca9-22 oral cancer cells through apoptosis, DNA damage and ROS induction. “Mutation Research - Genetic Toxicology and Environmental Mutagenesis”. 2012, 747(2), 253-258.
• Chien-Liang Lin, Ruei-Feng Chen, Jeff Yi-Fu Chen, Ying-Chieh Chu, Hui-Min Wang, Han-Lin Chou, Wei-Chiao Chang, Yao Fong , Wen-Tsan Chang, Chang-Yi Wu and Chien-Chih Chiu*. Protective effect of caffeic acid on paclitaxel induced anti-proliferation and apoptosis of lung cancer cells involves NF-κB pathway. “Int. J. Mol. Sci”.2012, 13 (5), 6235-6245. * Corresponding author.
• Wei-Ting Liao, Tsi-Shu Huang, Chien-Chih Chiu, Jian-Liang Pan, Shih-Shin Liang, Bing-Hung Chen, Shi-Hui Chen, Hui-Min Wang*, Shu-Wen Hsiao*. Biological properties of acidic cosmetic water from seawater. “Int. J. Mol. Sci”.2012, 13(5), 5952-5971.
• Chien-Chih Chiu, Han-Lin Chou, Pei-Fang Wu, Hui-Ming Wang*, Chung-Yi Chen*. Bio-functional constituents from the stems of Liriodendron tulipifera. “Molecules”. 2012, 17(4), 4357-4372.
• Kim SH, Huang CY, Tsai CY, Lu SY, Chien-Chih Chiu, Fang K. The aqueous extract of Prunella vulgaris suppresses cell invasion and migration in human liver cancer cells by attenuating matrix metalloproteinases. “Am J Chin Med”. 2012; 40(3), 643-56.
• Tzu-Rong Su, Jen-Jie Lin, Chien-Chih Chiu, Jeff Yi-Fu Chen, Jui-Hsin Su, Zhi-Jiao Cheng, Wen-Ing Hwang, Han Hsiang Huang§ and Yu-Jen Wu§. Proteomic investigation of anti-tumor activities exerted by sinularin against A2058 melanoma cells. “Electrophoresis”.2012, 33:1139-1152. SCI. IF: 3.569 
• Bing-Hung Chen*, Mei-Huei Hung, Jeff Yi-Fu Chen, Hsueh-Wei Chang, Meng-Lung Yu, Lei Wan, Fuu Jen Tsai, Tzu-Pin Wang, Tzu-Fun Fu, Chien-Chih Chiu*. Anti-allergic activity of grape seed extract (GSE) on RBL-2H3 mast cells. “Food Chemistry”. 2011 132(2):968-974.SCI. IF: 3.458  * Corresponding author.
• Hui-Min Wang, Chien-Chih Chiu, Pei-Fang Wu, Chung-Yi Chen*. Subamolide E from Cinnamomum subavenium induces sub-G1 cell cycle arrest, caspase-dependent apoptosis, and reduces migration ability of human melanoma cells. “Journal of Agricultural and Food Chemistry”. 2011; 59(15):8187-92. SCI. IF: 2.816
• Chau-Zen Wang, Mei-Ling Ho, Wen-Cheng Chen, Chien-Chih Chiu, Yung-Li Hung, Chih-Kuang Wang, Shun-Cheng Wu. Characterization and enhancement of chondrogenesis in porous hyaluronic acid-modified scaffolds made of PLGA (75/25) blended with PEI-grafted PLGA (50/50). “Materials Science and Engineerin: C”. 2011; 317:1343-51. SCI. IF: 2.18  
• Wei-Fan Chiang, Hsu-Chueh Ho, Hua-Yuan Chang, Chien-Chih Chiu, Yuh-Ling Chen, Tzyh-Chyuan Hour, Shu-Ju Chuang, Yu-Jen Wug, Hau-Ren Chen h, Jen-Hao Chen, Shyun-Yeu Liu, Chin-Li Lu, Jeff Yi-Fu Chen. Overexpression of Rho GDP-dissociation inhibitor alpha predicts poor survival in oral squamous cell carcinoma. “Oral Oncology”. 2011; 47(6):452-8.SCI. IF: 2.871  
• Chien-Chih Chiu, Po-Len Liu, Kuang-Jing Huang, Kuo-Feng Chang, Hui-Min Wang, Chon-Kit Chou, Jia-Shing Chen, Kang Fang, Yang-Chang Wu, Hsueh-Wei Chang. Goniothalamin inhibits growth of human lung cancer cells through DNA damage, apoptosis and reduced migration ability. “Journal of Agricultural and Food Chemistry”. 2011; 59(8):4288-93.SCI. IF: 2.816.
• Hun-Yu Tsai, Chien-Chih Chiu, Ping-Chih Lin, Su-Hwei Chen, Shih-Jer Huang, Li-Fang Wang*. Antitumor Efficacy of Doxorubicin Released from Crosslinked Nanoparticulate Chondroitin Sulfate/Chitosan Polyelectrolyte Complexes. “Macromolecular Bioscience”. 2011; 11(5):680-8. SCI. IF: 3.458.
• Kuo HC, Yu HR, Juo SH, Yang KD, Wang YS, Liang LD, Chen WC, Chang WP, Huang CF, Lee CP, Lin LY, Liu YC, Guo YC, Chien-Chih Chiu and Chang WC*. CASP3 gene single nucleotide polymorphism (rs72689236) and Kawasaki disease in Taiwanese children. “Journal of Human Genetics”. 2011;56(2):161-5.SCI.SCI. IF: 2.496  
• J.-C. Lee, .C.K Tseng, S.-F. Wu, F.-R. Chang, Chiu, Chien-Chih, Chiu and Y.-C. Wu. San-Huang-Xie-Xin-Tang extract suppresses hepatitis C virus replication and virus-induced cyclooxygenase-2 expression. “Journal of Viral Hepatitis”. 2011; 18(7):e315-24. SCI. IF: 3.502
• Chien-Chih Chiu, Yin Tzu Lin, Shuo Li Sun Kuo Hsun Sung and Li Fang Wang*. “Journal of Biomaterials Science”. 2011; 22(11):1487-507. SCI. IF: 1.842 
• Hui-Min Wang, Kuo-Chen Cheng, Shu-Wei Hsu, Hsi-An Chen, Cheng-Jung Lin, Wei-Cheng Fang, Tai-Feng Hsu, Chien-Chih Chiu, Hsueh-Wei Chang, Chung-Yi Chen, Chun-Hua Hsu and Alan Yueh-Luen Lee. Obtusilactone A and (-)-sesamin induce apoptosis in human lung cancer cells via inhibiting mitochondrial Lon protease and activating DNA damage checkpoints. “Cancer Science”. 2010; 101(12):2612-20. SCI. IF: 3.846
• Chien-Chih Chiu§, Bing-Hung Chen§, Tzyh-Chyuan Hour, Wei-Fan Chiang,Yu-Jen Wu, Ching-Yi Chen, Hau-Ren Chen, Po-Ting Chan, Shyun-Yeu Liu, Jeff Yi-Fu Chen*. Betel quid extract promotes oral cancer cell migration by activating a muscarinic M4 receptor-mediated signaling cascade involving SFKs and ERK1/2. “Biochemical and Biophysical Research Communications”. 2010; 399(1):60-5.SCI. IF: 2.595. § Equal contribution. 
• Jeff Yi-Fu Chen§, Chi-Ching Hwang§, Wei-Yi Chen, Jing-Ching Lee, Tzu-Fun Fu, Kang Fang, Ying-Chieh Chu, Ya-Lan Huang, Jia-Cheng Lin, Wen-Hui Tsai, Hsueh-Wei Chang, Bing-Hung Chen*, Chien-Chih Chiu*. Additive effects of C2-ceramide on Paclitaxel-induced premature senescence of human lung cancer cells. “Life Sciences”. 2010; 87(11-12):350-7. SCI. IF: 2.451 * Corresponding author.
• Hui-Min Wang, Jian-Liang Pan, Chun-Yen Chen, Chien-Chih Chiu, Mu-Hoe Yang, Hsueh-Wei Chang, Jo-Shu Chang. Identification of anti-lung cancer extract from Chlorella vulgaris C-C by antioxidant property using supercritical carbon dioxide extraction.“Process Biochemistry”.2010; 45(12):1865-72. SCI. IF: 2.648 . 
• Po-Len Liu, Jong-Rung Tsai, Chien-Chih Chiu, Jhi-Jhu Hwang, Shah-Hwa Chou, Chih-Kuang Wang, Shu-Jing Wu, Yuh-Lien Chen, Wen-Chi Chen, Yung-Hsiang Chen, Inn-Wen Chong. Decreased Expression of Thrombomodulin is correlated with Tumor Cell Invasiveness and Poor Prognosis in Non-small Cell Lung Cancer. “Molecular Carcinogenesis”.2010; 49(10):874-81. SCI. IF: 3.265  
• Ching-Ming Chien, Shang-Yu Chang, Kuei-Li Lin, Chien-Chih Chiu, Long-Sen Chang, Shinne-Ren Lin. Taiwan cobra cardiotoxin III inhibits Src kinase leading to apoptosis and cell cycle arrest of oral squamous cell carcinoma Ca9-22 cells. “Toxicon”. 2010; 56(4):508-20. SCI. IF: 2.451
• Chien-Chih Chiu*, Jeff Yi-Fu Chen, Kuei-Li Lin, Chi-Jung Huang, Wan-Yu Chen, Yi-Han Lo, Yi-Lan Chen, Chih-Hua Tseng, Yeh-Long Chen*, Shinne-Ren Lin. p38 MAPK and NF-κB pathways are involved in Naphtho[1,2-b] furan-4,5-dione induced anti-proliferation and apoptosis of human hepatocellular carcinoma. “Cancer Letters”. 2010; 295(1):92-9 SCI. IF: 4.864  *First and Corresponding author. 
• Ching-Yu Yen§, Chien-Chih Chiu§, Fang-Rong Chang, Jeff Yi-Fu Chen, Chi-Ching Hwang, You-Cheng Hseu, Hsin-Ling Yang, Alan Yueh-Luen Lee, Ming-Tz Tsai, Zong-Lun Guo, Yu-Shan Cheng, Yin-Chang Liu, Yu-Hsuan Lan, Yu-Ching Chang, Ying-Chin, Ko, Hsueh-Wei Chang*, and Yang-Chang Wu*. 4β-hydroxywithanolide E from Physalis peruviana (golden berry) inhibits growth of human lung cancer cells through DNA damage, apoptosis and G2/M arrest. “BMC Cancer”. 2010; 10:46. SCI. IF: 3.15 § Equal contribution.  
• Yi-Hsun Chang, Chau-Zen Wang, Chien-Chih Chiu, Lea-Yea Chuang, Chi-Ching Hwang. Contributions of Active Site Residues to Cofactor Binding and Catalysis of 3α-Hydroxysteroid Dehydrogenase/Carbonyl Reductase. “Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics”. 2010;1804(1):235-41 SCI. IF= 2.773
• Chien-Chih Chiu§, Hsueh-Wei Chang§, Da-Wei Chuang, Fang-Rong Chang, Yu-Ching Chang, Su-Shuo Lee, Yu-Shan Cheng, Chih-Kuang Wang, Jeff Yi-Fu Chen, Yin-Chang Liu, Yang-Chang Wu*. Fern plant-derived protoapigenone leads to DNA damage, apoptosis and G2/M arrest in lung cancer cell line H1299. “DNA and Cell Biology”. 2009; 28(10):501-6. SCI. IF: 2.159 . § Equal contribution.  
• Tseng MY, Liu SY, Chen HR, Wu YJ, Chien-Chih Chiu, Chiang WF, Liu YC, Lu CY, Joy YS, and Chen JYF*. Serine protease inhibitor-1 (SERPIN) B1 promotes oral cancer cell mobility and is over-expressed in invasive squamous cell carcinoma. “Oral Oncology”. 2009; 45(9):771-6 SCI. IF: 2.871  
• Chien-Chih Chiu, Kuei-Li Lin, Ching-Ming Chien, Long-Sen Chang, Shinne-Ren Lin*. Effects of cardiotoxin III on NF-κB function, proliferation and apoptosis in human breast MCF-7 cancer cells. “Oncology Research”. 2009;17(7):311-21. SCI. IF: 0.826  

Conferences 

• Han-Lin Chou, Hurng-Wern Huang, Chien-Chih Chiu*. Chloroquine synergistically promotes C2-ceramide induced apoptosis of non-small cell lung cancer cells via inhibiting sirt1 expression. 2013 Taiwan Zebrafish Symposium Dec. 7. Institute of Biomedical Sciences Academia Sinica. #P22. (The best poster award).  台灣斑馬魚研討會 
• Mei-Jei Lu and Chien-Chih Chiu*. The effect of Akt-targeting compounds on proliferation and apoptosis of lung cancer cells in zebrafish xenografts. 2013 Taiwan Zebrafish Symposium Dec. 7. Institute of Biomedical Sciences Academia Sinica.#P23. 台灣斑馬魚研討會
• Chien Chih, Chiu and  Bing-Hung Chen*. Anti-allergic activity of grape seed extract (GSE) on RBL-2H3 mast cells. The 19th Symposium of Young Asian Biochemical Engineer’s Community (YABEC). (ORAL#1). 2013. Urumqi, China.
• Chon Kit, Chou, Chien Chih, Chiu*. The 19th Symposium of Young Asian Biochemical Engineer’s Community (YABEC). (POSTER#PD1). YABEC 2013. Urumqi, China. (YABEC *best poster award)
  Han Lin, Chou, Chien Chih, Chiu*. The 19th Symposium of Young Asian Biochemical Engineer’s Community (YABEC). (POSTER#PD2). 2013. Urumqi, China. 
• Yin-Chieh Lin, Jeff Yi-Fu Chen, Chien-Chih Chiu*. The inhibitory effects of sirtinol, a sirtuin inhibitor on invasion of non-small cell lung cancer cells via Src signaling. The 18th Symposium of Young Asian Biochemical Engineer’s Community (YABEC) 2012. (ORAL: O-CD-7).
• Pin-Hsuan Wu, Jeff Yi-Fu Chen, Yeh-Long Chen, Chien-Chih Chiu*. Naphtho[1,2-b] furan-4,5-dione, a naphthoquinone derivative induces anti-cell growth and anti-migration in non-small cell lung cancer by inhibiting topoisomerase II. Bio-IT WORLD ASIA in Marina Bay Sands Hotel, Singapore, in June 6-8, 2012.(*corresponding). (POSTER #6) Session of Drug Discovery and Bioinformatics.
• Yuli C. Chang, Shih-Ya Hung, Chien-Chih Chiu, Wen-Lin Chan, Wen-Hsin Chang, Shou-Mei Wu, Ya-Sian Chang, Chung-Yee Yuo, Ta-Chih Liu, Wen-Kuang Yang, Jan-Gowth Chang*. Participation of a XIST-related small RNA in the formation of the K-RAS G-quadruplex. Non-Coding RNAs (Z1) Keystone symposia conference. Snowbird, Utah, USA, in March 31-April 5. 2012
• Yin-Chieh Lin, Han-Lin Chou, Chien-Chih Chiu＊. The inhibitory effects of sirtuin1 inhibitor, sirtinol on migration and anchorage independent growth of lung cancer cells. (POSTER #85) SCMB2012. 第20 屆細胞及分子生物新知研討會 (*corresponding)
• Han-Lin Chou, Feng-Wei Chen, Xin-Ping Tang, Hurng-Wern Huang＊, Chiu, Chien-Chih＊. The synergistic effect of C2-ceramide in Doxorubicin was induced senescence of non-small-cell lung cancer (NSCLC). (POSTER #57) SCMB2012. 第20 屆細胞及分子生物新知研討會 (*corresponding)
• Chon Kit Chou, Han-Lin Chou, Feng-Wei Chen, Chien-Chih Chiu*.The Novel Function of BubR1 in Migration Ability of Non-Small Cell Lung Cancer Cells. (POSTER #121) SCMB2012. 第20 屆細胞及分子生物新知研討會(*corresponding)
• Huei-Ting Hu, Hsueh-Wei Chang*, Lian-Je Hwang, Hsin-Yu Fang, Chien-Chih Chiu*. Effect of ferulic acid on anti-oxidation and cell proliferation of human lung cancer cells. (POSTER #95) SCMB 2012. 第20 屆細胞及分子生物新知研討會. (*corresponding)
• Pin-Hsuan Wu, Chien-Chih Chiu*, Yeh-Long Chen, Hsueh-Wei Chang. A novel naphthoquinone derivative-induced apoptosis and growth inhibition of human non-small cell lung cancer (NSCLC). (POSTER #27) SCMB2012. 第20 屆細胞及分子生物新知研討會. (*corresponding)
• Chiu-Chien Chiu*, Chon-Kit Chou, Han-Lin Chou. Goniothalamin inhibits growth of human lung cancer cells through DNA damage, apoptosis and reduced migration ability. (Oral and POSTER) (POSTER # F14). The 17th Symposium of Young Asian Biochemical Engineer’s Community (YABEC) in Incheon, Korea in Oct 7-9,2011. (*corresponding)
• Kuo-Feng Chang, Hsueh-Wei Chang, Tso-Wen Wang, Chih-Hua Tseng, Yeh-Long Chen, Chien-Chih Chiu*. The mechanistic study of quinoline-derivative-induced apoptosis and growth inhibition of lung cancer.(POSTER #160) SCMB 2011. 第19屆細胞及分子生物新知研討會. (*corresponding)
• Kuo-Feng Chang, Hsueh-Wei Chang, Wan-Ju Chou, Chih-Hua Tseng, Yeh-Long Chen, Chien-Chih Chiu*. The quinoline-derivative DFIQ induced apoptosis and growth inhibition of lung cancer. SCMB 2011. 第19屆細胞及分子生物新知研討會. (*corresponding)
• Han-Lin Chou, Hsueh-Wei Chang, Pi-Chuan Hsieh, Xin-Ping Tang, Feng-Wei Chen, Hurng-Wern Huang*,Chiu, Chien-Chih*. Role of exogenous ceramides in modulating the expression of human type III deacetylase SIRT-1 and SIRT-2 of human non-small cell lung cancer (NSCLC) cells. (POSTER #86) SCMB 2011.第19屆細胞及分子生物新知研討會. (*corresponding)
• Yin-Chieh Lin, Jeff Yi-Fu Chen, Hsueh-Wei Chang*, Chien-Chih Chiu*. The modulation of cell proliferation induced by exogenous ceramide in human breast cancer cells. (POSTER #114) SCMB 2011. 第19屆細胞及分子生物新知研討會. (*corresponding)
• Huei-Ting Hu, Hsueh-Wei Chang, Lian-Je Hwang, Hsin-Yu Fang, Chien-Chih Chiu*. Effect of feruloyl xylo-oligosaccharides on antioxidant activity and cell migration in human lung cancer H1299 cells. (POSTER #133) SCMB 2011. 第19屆細胞及分子生物新知研討會. (*corresponding)
• Pin-Hsuan Wu, Chien-Chih Chiu*, Yeh-Long Chen and Hsueh-Wei Chang*. NFD inhibits cell proliferation and migration of human non-small cell lung cancer (NSCLC) cell through DNA damage and reduced migration ability. (POSTER #50) SCMB 2011. 第19 屆細胞及分子生物新知研討會. (*corresponding)
• Chon-kit Chou, Han-Lin Chou, Pin-Hsuan Wu, Hsueh-Wei Chang* and Chien-Chih Chiu*. The effect of spindle assembly checkpoint kinase BubR1 on cellular migration in oral squamous cell carcinoma. (POSTER #171) SCMB 2011. 第19 屆細胞及分子生物新知研討會. (*corresponding)
• Kuang-Jing Huang, Chien-Chih Chiu*, Fang-Rong Chang, Yang-Chang Wu, Hsueh-Wei Chang*. AN10 is a potential natural product-derived drug against oral cancer. SCMB 2011. 第19 屆細胞及分子生物新知研討會.(*corresponding)
• Kuang-Jing Huang, Chien-Chih Chiu*, Fang-Rong Chang, Yang-Chang Wu, Hsueh-Wei Chang*. AN10 inhibits growth of human lung cancer cells through DNA damage, apoptosis and reduced migration ability. (POSTER #256) SCMB 2011. 第19屆細胞及分子生物新知研討會. (*corresponding)
• Kuang-Jing Huang, Chien-Chih Chiu*, Fang-Rong Chang, Yang-Chang Wu, Hsueh-Wei Chang*. SCMB 2011. AN37 is a potential natural product-derived drug against oral cancer.第19屆細胞及分子生物新知研討會.
• Jeff Yi-Fu Chen, Chien-Chih Chiu, Yu-Jen Wu, Hau-Ren Chen. Betel Quid Extract Promotes Oral Cancer Cell Migration by Activating a Muscarinic M4 Receptor-Mediated Signaling Cascade Involving ERK1/2 and SFKs. 4th World Congress of International Federation of Head and Neck Oncologic Societies in Seoul, Korea in June 15-19, 2010.
• Guang-Jing Huang, Ming-Tz Tsai, Chon-Kit Chou, Chien-Chih Chiu, Yang-Chang Wu, Hsueh-Wei Chang. Growth inhibition of lung cancer cell using herb-derived compound AN10 based on cell migration analysisSCMB 2010. 第18屆分子生物學會冬令營
• Yung-Lan Su, Yi-Han Lo, Wan-Yu Chen, Tsung-Lun Kuo, Jan-Gowth Chang*, Chien-Chih Chiu*.Characterization of ectopic expression of nuclear export factor (NXF) in human hepatoma cells Huh-7 (POSTER # P331) The Twenty-fourth Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan. (Mar. 21-22, 2009). 第24屆生物醫學聯合學術年會 (*corresponding)
• Chien-Chih Chiu* (Oral Presentation # O46 ). Effects of ectopically expressed nuclear export factor (NXF) on cell migration and adhesion in human hepatoma cells. The Twenty-fourth Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan, Mar. 21-22, 2009. 第24屆生物醫學聯合學術年會 (*oral and corresponding)
• Pi-Chuan Hsieh, Chien-Chih, Chiu, Jan-Gowth Chang, Sheng-Fung Lin.BubR1 Gene Is Involved in Ceramide Induced Mitotic Arrest in Malignant Cancer Cells.(May 2007). 第12屆台灣癌症聯合學術年會
• Ying-Chieh Chu, Kai-Li Su, Min-Tsui Wu, Chien-Chih Chiu*. The effects of caffeic acid in anticancer drug-induced human non-small cell lung cancer (NSCLC) cells. (Mar 2007). 第22屆生物醫學年會 (*corresponding)